alexa Field Investigations of Glyphosate in Urine of Danish Dairy Cows
ISSN: 2161-0525

Journal of Environmental & Analytical Toxicology
Open Access

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Research Article

Field Investigations of Glyphosate in Urine of Danish Dairy Cows

Monika Krüger1, Wieland Schrödl1, Jürgen Neuhaus1 and Awad Ali Shehata1,2,3*

1Institute of Bacteriology and Mycology, Veterinary Faculty, University of Leipzig, An den Tierkliniken 29, D-04103 Leipzig, Germany

2Avian and Rabbit Diseases Department, Faculty of Veterinary Medicine, Minoufiya University, Egypt

3Albrecht Daniel Thaer-Institute of Agronomy, University Leipzig, Leipzig, Germany

*Corresponding Author:
Awad Shehata
Institute of Bacteriology and Mycology
Faculty of Veterinary Medicine
Leipzig University, Germany
Tel: +49 341 973 8181
Fax: +49 341 973 8199
E-mail: [email protected]

Received date: July 25, 2013; Accepted date: August 21, 2013; Published date: August 23, 2013

Citation: Krüger M, Schrödl W, Neuhaus J, Shehata AA (2013) Field Investigations of Glyphosate in Urine of Danish Dairy Cows. J Environ Anal Toxicol 3:186. doi: 10.4172/2161-0525.1000186

Copyright: © 2013 Krüger M, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

 

Abstract

In the present study, thirty dairy cows from each of eight Danish dairy farms were investigated for excretion of glyphosate in urine. Blood serum parameters indicative of cytotoxicity as alkaline phosphatase (AP), glutamate dehydrogenase (GLDH), glutamate oxaloacetate transaminase (GOT), creatinine kinase CK), nephrotoxicity, (urea, creatine), cholesterol and the trace elements as manganese (Mn), cobalt (Co), selenium (Se), copper (Cu) and zinc (Zn) were investigated. All cows excreted glyphosate in their urine but in varying concentrations. Increased levels of GLDH, GOT and CK in cows from all farms demonstrate a possible effect of glyphosate on liver and muscle cells. High urea levels in some farms could be due to nephrotoxicity of glyphosate. Also the unexpected very low levels of Mn and Co were observed in all animals which could be explained due to a strong mineral chelating effect of glyphosate. In contrast the mean levels of Cu, Zn and Se were within the normal reference range. In conclusion, this study gives the first documentation to which extent Danish dairy cattle are exposed to Glyphosate and its impact on blood parameters.

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