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Hindi Case Report
First Report of Three Major Oncogenic Viruses: Human Papillomavirus, Epstein-Barr Virus And Merkel Cell Polyomavirus in Penile Cancer
| Baez CF1, da Rocha WM2, Afonso LA2, Carestiato FN2, Guimarães MAAM1, Cavalcanti SMB2 and Varella RB2* | |
| 1Department of Preventive Medicine, Hospital Universitário Clementino Fraga Filho, Universidade Federal do Rio do Janeiro, Brazil | |
| 2Department of Microbiology and Parasitology, Universidade Federal Fluminense, Brazil | |
| Corresponding Author : | Rafael B Varella Laboratory of Virology Department of Microbiology and Parasitology Universidade Federal Fluminense, Brazil Tel: 55 21 2560-8344 E-mail: rvarella@id.uff.br |
| Received: July 16, 2015 Accepted: September 03, 2015 Published: September 09, 2015 | |
| Citation: Baez CF, da Rocha WM, Afonso LA, Carestiato FN, Guimarães MAAM et al. (2015) First Report of Three Major Oncogenic Viruses: Human Papillomavirus, Epstein-Barr Virus And Merkel Cell Polyomavirus in Penile Cancer. J Infect Dis Ther 4:233. doi:10.4172/2332-0877.1000233 | |
| Copyright: © 2015 Baez CF, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. | |
| Related article at Pubmed, Scholar Google | |
Abstract
We report here in first hand a case of triple infection caused by oncogenic viruses: HPV16, EBV-2 and MCPyV, in a squamous cell carcinoma of penis with an unfavorable outcome. Although reports on multiple viral infections in tumors are increasing, we do not know whether they are simply co-detected in the tissue or playing a synergistic role in the tumorigenesis. Studies addressing a putative co-stimulatory effect among these agents are needed in order to improve our comprehension of cell transformation.
