alexa Fluid Optimization in Liver Surgery | OMICS International | Abstract
ISSN: 2155-6148

Journal of Anesthesia & Clinical Research
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Research Article

Fluid Optimization in Liver Surgery

Levantesi Laura1, Oggiano Marco1, Fiorini Federico1, Sessa Flaminio1, De Waure Chiara2*, Congedo Elisabetta1 and De Cosmo Germano1

1Institute of Anaesthesiology and Intensive Care, Catholic University of Sacred Heart, Rome, Italy

2Department of Public Health, Catholic University of Sacred Heart, Rome, Italy

*Corresponding Author:
Laura Levantesi
Institute of Anaesthesiology and Intensive Care
Catholic University of Sacred Heart
Rome, Italy
Tel: 039 0630154507
Email: [email protected]

Received date: July 09, 2016; Accepted date: August 26, 2016; Published date: August 31, 2016

Citation: Levantesi L, Oggiano M, Fiorini F, Sessa F, De Waure C, et al. (2016) Fluid Optimization in Liver Surgery. J Anesth Clin Res 7:657. doi:10.4172/2155-6148.1000657

Copyright: Levantesi L, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.


Background: A previous study investigated the value of adding a dietitian to a geriatric discharge Liaison-Team. The scope of this study was to explore the possible economic savings of this.

Methods: Patients, 70+ and at nutritional risk, were randomized to receive discharge Liaison-Team either with (intervention group, IG) or without a dietitian (control group, CG). The IG received three home visits by the dietitian during a 12-week period. Data included in the economic analysis was time spent by the dietitian, use of oral nutritional supplements (ONS) and number of hospitalization days.

Results: Of the 71 included patients, 34 were in the IG, 30 patients received all three dietitian visits. Cumulated number of hospitalization days was 172 in the IG and 415 in the CG. Use of ONS was 48% in the IG and 17% in the CG (P=0.001). Estimated cost for the dietitian and ONS combined in the IG was €9,416 compared to €1,150 (ONS only) in the CG. For hospitalizations, estimated cost was €92,020 in the IG and €220,025 in the CG. Cost savings added up to €3,048 per patient in the IG.

Conclusion: Adding a dietitian to a geriatric discharge Liaison-Team decreased health care costs.

Study’s purposes: To reduce bleeding, hepatectomies are usually performed maintaining low central pressure (CVP) combined with extrahepatic control flow and this management can lead hemodynamic instability and reduction in oxygen delivery. This study analyzes hemodynamic changes and so the derived fluid management, in patients undergoing liver resection, through the Vigileo/FloTrac system. Basic procedures: Seventeen patients were included. Low CVP, below 4 mmHg, was reached by loop diuretics. Hemodynamic parameters were recorded and blood gas analysis was also performed. At the end of resection, fluid replacement was carried out with 500 ml of crystalloid solution in 20 minutes evaluating changes in CVP, Cardiac Index (CI) and Stroke Volume Variation (SVV). Main findings: During Pringle maneuver, Cardiac Index resulted stable through a modification in heart rate and vascular resistances (p<0.01). Only SVV significantly changed during Pringle maneuver (p=0.03) and not CVP (p=0.8). In all patients the oxygen delivery was maintained upper 600 ml/min/m2. Fluid optimization was performed with 1917 ml ± 1161 ml of crystalloid solution with a significant reduction in SVV (p<0.01) about 7% despite a CVP of 5 mmHg. Conclusions: We suppose that SVV can replace CVP in major hepatectomy management. Regarded results we can conclude that a good peripheral perfusion can be reached also with a fluid restrictive regimen avoiding overload and postoperative edema.


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