alexa Fluid Replacement Strategy in Severe Acute Pancreatitis
ISSN: 2165-7092

Pancreatic Disorders & Therapy
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Review Article

Fluid Replacement Strategy in Severe Acute Pancreatitis

Pezzilli R*
Pancreas Unit, Department of Digestive Diseases and Internal Medicine, Sant’Orsola-Malpighi Hospital, Bologna, Italy
Corresponding Author : Raffaele Pezzilli
Pancreas Unit
Department of Digestive System Diseases and Internal Medicine
Sant’Orsola-Malpighi Hospital
Via G Massarenti, 940138 Bologna, Italy
Tel: +39-051-636-4148
Fax: +39-051-636-4148
E-mail: [email protected]
Received December 03, 2012; Accepted January 24, 2013; Published January 31, 2013
Citation: Pezzilli R (2013) Fluid Replacement Strategy in Severe Acute Pancreatitis. Pancreatic Dis Ther S2:001. doi:10.4172/2165-7092.S2-001
Copyright: © 2013 Pezzilli R. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.


Adequate fluid resuscitation, pain control and organ support represent the cornerstones of treatment for acute pancreatitis. In this review, following questions will be answered on the basis of recent literature data: 1.What is the adequate volume of fluid to be administered and when should it be administered? 2. What type of fluid should be utilized? 3. What are the contraindications of an excessive amount of fluid? The suggestion to the practicing physician is that the amount of fluid administered patients with acute pancreatitis should be in the range of 3.1-4.1 l during the initial 24 hours after admission. The fluids used should be the lactated Ringer’s solution because the pH is more balanced than simple saline solution. Caution should be recommended regarding early fluid administration; the fluid should be administered under continuous monitoring.

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