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Follicular Thyroid Carcinoma with Insular Component Metastatic to the Sphenoid Wing | OMICS International | Abstract
ISSN: 2155-9570

Journal of Clinical & Experimental Ophthalmology
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Case Report

Follicular Thyroid Carcinoma with Insular Component Metastatic to the Sphenoid Wing

Eve E. Moscato1,2, H. Jane Kim1, M. Reza Vagefi1 and Rona Z. Silkiss2
1Department of Ophthalmology, University of California, San Francisco, CA, USA
2Department of Ophthalmology, California Pacific Medical Center, San Francisco, CA, USA
Corresponding Author : Eve E. Moscato, M.D.
Department of Ophthalmology
University of California 2100 Webster Street
Suite 214, San Francisco, CA 94115, USA
E-mail: [email protected]
Received September 09, 2012; Accepted October 27, 2012; Published November 02, 2012
Citation: Moscato EE, Kim HJ, Vagefi MR, Silkiss RZ (2012) Follicular Thyroid Carcinoma with Insular Component Metastatic to the Sphenoid Wing. J Clin Exp Ophthalmol 3:251. doi:10.4172/2155-9570.1000251
Copyright: © 2012 Moscato EE, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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A 60-year-old woman with a history of follicular thyroid carcinoma with insular component presented with a large asymptomatic sphenoid wing mass discovered on routine surveillance. Therapeutic options including observation, surgical excision, radiation therapy, and I-131 therapy were initially debated. Each option presented potential morbidity. The patient initially underwent treatment with iodine-131 (I-131) with a decrease in size of the mass over 8 months. Subsequent MRI at 11 months revealed enlargement of the sphenoid wing mass with involvement of the orbital apex, cavernous sinus, and the middle cranial fossa. The patient ultimately underwent surgical resection and debulking via a frontotemporal orbitozygomatic approach. Although rare, follicular thyroid carcinoma with insular features often has an aggressive clinical course with local invasion and distant metastases. It carries a poor prognosis and can be difficult to treat due to a lack of available treatment protocols and the known morbidity of current therapies.

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