Follicular Thyroid Carcinoma with Insular Component Metastatic to the Sphenoid Wing
|Eve E. Moscato1,2, H. Jane Kim1, M. Reza Vagefi1 and Rona Z. Silkiss2|
|1Department of Ophthalmology, University of California, San Francisco, CA, USA|
|2Department of Ophthalmology, California Pacific Medical Center, San Francisco, CA, USA|
|Corresponding Author :||Eve E. Moscato, M.D.
Department of Ophthalmology
University of California 2100 Webster Street
Suite 214, San Francisco, CA 94115, USA
E-mail: [email protected]
|Received September 09, 2012; Accepted October 27, 2012; Published November 02, 2012|
|Citation: Moscato EE, Kim HJ, Vagefi MR, Silkiss RZ (2012) Follicular Thyroid Carcinoma with Insular Component Metastatic to the Sphenoid Wing. J Clin Exp Ophthalmol 3:251. doi:10.4172/2155-9570.1000251|
|Copyright: © 2012 Moscato EE, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.|
|Related article at
Pubmed Scholar Google
A 60-year-old woman with a history of follicular thyroid carcinoma with insular component presented with a large asymptomatic sphenoid wing mass discovered on routine surveillance. Therapeutic options including observation, surgical excision, radiation therapy, and I-131 therapy were initially debated. Each option presented potential morbidity. The patient initially underwent treatment with iodine-131 (I-131) with a decrease in size of the mass over 8 months. Subsequent MRI at 11 months revealed enlargement of the sphenoid wing mass with involvement of the orbital apex, cavernous sinus, and the middle cranial fossa. The patient ultimately underwent surgical resection and debulking via a frontotemporal orbitozygomatic approach. Although rare, follicular thyroid carcinoma with insular features often has an aggressive clinical course with local invasion and distant metastases. It carries a poor prognosis and can be difficult to treat due to a lack of available treatment protocols and the known morbidity of current therapies.