Formulation, Evaluation and Mathematical Modelling of Clopidogrel Bisulphate & Aspirin Immediate Release Bilayer TabletsAbdul Althaf S*, Sailaja PB and Ashwin Kumar M
Division of Pharmacy, Sri Venkatswara University, Tirupati, Andhra Pradesh, India
- *Corresponding Author:
- Abdul Althaf S
Division of Pharmacy
Sri Venkatswara University
Tirupati, Andhra Pradesh, India
E-mail: [email protected]
Received date: November 06, 2012; Accepted date: November 19, 2012; Published date: November 25, 2012
Citation: Abdul Althaf S, Sailaja PB, Ashwin Kumar M (2012) Formulation, Evaluation and Mathematical Modelling of Clopidogrel Bisulphate & Aspirin Immediate Release Bilayer Tablets. Pharmaceut Anal Acta 3:194. doi: 10.4172/2153-2435.1000194
Copyright: © 2012 Abdul Althaf S, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
The use of a fixed-dose combination (Clopidogrel bisulphate and Aspirin) tablet instead of the individual administration of the two compounds is expected to be more convenient to patients (and thus to improve compliance) by limiting the number of tablets they need to take. Therefore, to improve patient compliance and to decrease the incidence of adverse effects and side effects, Clopidogrel bisulphate and Aspirin are together formulated as an immediate release bilayer tablet. This study is intended to produce an immediate release bilayer tablets using solid dispersion technique. The prepared tablets were evaluated and subjected to dissolution studies.