Frequency of Discrepancy between Scintigraphy Reports and TSH Dosage
- corresponding Author:
- Daniele Di Biagio
Department of Diagnostic Imaging and Interventional Radiology
Molecular Imaging and Radiotherapy
University of Rome “Tor Vergata”, Rome, Italy
E-mail: [email protected]
Received Date: October 02, 2012; Accepted Date: October 26, 2012; Published Date: October 28, 2012
Citation: Schillaci O, Modoni S, Tavolozza M, Travascio L, Lacanfora A, et al. (2012) Frequency of Discrepancy between Scintigraphy Reports and TSH Dosage. Endocrinol Metab Synd 1:108. doi: 10.4172/2161-1017.1000108
Copyright: © 2012 Schillaci O, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Objective: The purpose of the study was to analyze the discrepancy observed between scintigraphic reports and hormonal dosages.
Methods: Eighty-four consecutive patients undergone thyroid scan with 99mTc were included in this study. 6/84 pts also underwent a 131I scan to compare discordant TSH value and thyroid scan result.
Results: Discrepancy in our series due to the absence of focal areas of thyroid hyperfunction was found in 15/84 patients with subclinical hyperthyroidism, defined by standard free fractions (FT3 and FT4) and TSH inhibited or anyway substandard (18% of all cases, 48% of patients with low TSH). In 11/84 patients (13% of all cases, 21% of patients with normal TSH value) a “hot” nodule was found without hormonal values suggestive of a frank or subclinical hyperthyroidism.
Conclusion: In cases with TSH below the normal range as there is often in front of the non-detection of nodules functionally independent. Further studies are needed to identify the coexistence of factors other than those already known, that play a role in regulating TSH. On the other hand the unexpected feedback of “hot” nodules with hormonal tests perfectly normal suggest a low intake of iodine in the diet; infact a low intake of iodine cannot produce enough thyroid hormone so high as to trigger the pituitary feed-back, even in areas of functional autonomy.