alexa GeneNarrator: Mining the Literaturome for Relations Among Genes
ISSN: 0974-276X

Journal of Proteomics & Bioinformatics
Open Access

Like us on:
OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Research Article

GeneNarrator: Mining the Literaturome for Relations Among Genes

Jing Ding1, Daniel Berleant2*, Jun Xu3, Kenton Juhlin4, Eve Wurtele5, Andy Fulmer6

1Information Warehouse, Ohio State University Medical Center, 410 W. 10th Ave., Columbus, Ohio, 43210, USA, [email protected], (614) 293-0776, fax (614) 293-2210

2Department of Information Science, University of Arkansas at Little Rock, 2801 University Ave., Little Rock, Arkansas, 72204, USA, [email protected], (501) 683-7056, fax (501) 683-7049

3Miami Valley Laboratories, The Procter and Gamble Company, 11810 East Miami River Rd., Ross, Ohio, 45061, USA, [email protected]

4Miami Valley Laboratories, The Procter and Gamble Company, 11810 East Miami River Rd., Ross, Ohio, 45061, USA, [email protected]

5Department of Genetics, Development and Cell Biology, Iowa State University, Ames, Iowa, 50011, USA, [email protected]

6Miami Valley Laboratories, The Procter and Gamble Company, 11810 East Miami River Rd., Ross, Ohio, 45061, USA, [email protected]

*Corresponding Author:
Dr. Daniel Berleant
Department of Information Science
University of Arkansas at Little Rock
2801 University Ave., Little Rock
Arkansas, 72204, USA
Tel: (501) 683-7056
Fax: (501) 683-7049
E-mail: [email protected]

Received Date: July 07, 2009; Accepted Date: August 23, 2009; Published Date: August 24, 2009

Citation: Ding J, Berleant D, Xu J, Juhlin K, et al. (2009) GeneNarrator: Mining the Literaturome for Relations Among Genes. J Proteomics Bioinform 2: 360-371. doi: 10.4172/jpb.1000096

Copyright: © 2009 Ding J, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

 

Abstract

The rapid development of microarray and other genom ic technologies now enables biologists to monitor t he expression of hundreds, even thousands of genes in a single experiment. Interpreting the biological m eaning of the expression patterns still relies largely on biologist's domain knowledge, as well as on information collected from the literature and various public databases. Yet i ndividual experts’ domain knowledge is insufficient for large data sets, and collecting and analyzing this information manually from the literature and/or public databases is tedious and time-consuming. Computer-aided functional analy sis tools are therefore highly desirable.

We describe the architecture of GeneNarrator, a tex t mining system for functional analysis of microarr ay data. This system’s primary purpose is to test the feasib ility of a more general system architecture based o n a two-stage clustering strategy that is explained in detail. Gi ven a list of genes, GeneNarrator collects abstract s about them from PubMed, then clusters the abstracts into funct ional topics in a first clustering stage. In the s econd clustering stage, the genes are clustered into groups based on similarities in their distributions of occurrence across topics. This novel two-stage architecture, the primary cont ribution of this project, has benefits not easily p rovided by one- stage clustering.

Keywords

Share This Page

Additional Info

Loading
Loading Please wait..
 
Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri, Food, Aqua and Veterinary Science Journals

Dr. Krish

[email protected]

1-702-714-7001 Extn: 9040

Clinical and Biochemistry Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Business & Management Journals

Ronald

[email protected]

1-702-714-7001Extn: 9042

Chemical Engineering and Chemistry Journals

Gabriel Shaw

[email protected]

1-702-714-7001 Extn: 9040

Earth & Environmental Sciences

Katie Wilson

[email protected]

1-702-714-7001Extn: 9042

Engineering Journals

James Franklin

[email protected]

1-702-714-7001Extn: 9042

General Science and Health care Journals

Andrea Jason

[email protected]

1-702-714-7001Extn: 9043

Genetics and Molecular Biology Journals

Anna Melissa

[email protected]

1-702-714-7001 Extn: 9006

Immunology & Microbiology Journals

David Gorantl

[email protected]

1-702-714-7001Extn: 9014

Informatics Journals

Stephanie Skinner

[email protected]

1-702-714-7001Extn: 9039

Material Sciences Journals

Rachle Green

[email protected]

1-702-714-7001Extn: 9039

Mathematics and Physics Journals

Jim Willison

[email protected]

1-702-714-7001 Extn: 9042

Medical Journals

Nimmi Anna

[email protected]

1-702-714-7001 Extn: 9038

Neuroscience & Psychology Journals

Nathan T

[email protected]

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

John Behannon

[email protected]

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

[email protected]

1-702-714-7001 Extn: 9042

 
© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
adwords