alexa Genetic Aspects of Cleft Lip and Palate – A Review
ISSN: 2376-0311

JBR Journal of Clinical Diagnosis and Research
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Review Article

Genetic Aspects of Cleft Lip and Palate – A Review

Ravi Teja Chitturi1*, Baddam Venkat Ramana Reddy2, Kattapagari Kiran Kumar3, Poosarala Chandrashekar4, Kantheti Lalith Prakash Chandra4 and Gontu Sridhar Reddy4

1Senior Lecturer, Department of Oral Pathology, SIBAR Institute of Dental Sciences, Guntur, Andhra Pradesh, India

2Professor and HOD, Department of Oral Pathology, SIBAR Institute of Dental Sciences, Guntur, Andhra Pradesh, India

3Professor, Department of Oral Pathology, SIBAR Institute of Dental Sciences, Guntur, Andhra Pradesh, India

4Reader, Department of Oral Pathology, SIBAR Institute of Dental Sciences, Guntur, Andhra Pradesh, India

Corresponding Author:
Ravi Teja Chitturi
Senior Lecturer, Department of Oral Pathology
SIBAR Institute of Dental Sciences
Guntur, Andhra Pradesh, India-522509
Tel: +91 – 9676767387
E-mail: [email protected]

Received date: April 28, 2014; Accepted date: September 08, 2014; Published date: September 15, 2014

Citation: Chitturi RT, Reddy BVR, Kumar KK, Chandrashekar P, Chandra KLP, et al. (2014) Genetic Aspects of Cleft Lip and Palate – A Review. J Clin Diagn Res 3:111. doi:10.4172/2376-0311.1000111

Copyright: © 2014 Chitturi RT, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

 

Abstract

Craniofacial abnormalities especially Cleft Lip and Palate (CLP) are considered to be one of the most commonly occurring birth defects in humans. CLP is considered to be a very important disorder to be understood because of the the complications it produces in an infant. Recent advances in molecular techniques has given a good insight into the various changes that occur at a genetic level, thus shedding some light on the pathogenesis of CLP. This review aims to give the reader an uptodate information regrading various genes that are involved in oro facial clefting especially CLP.

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