alexa Genetic Polymorphism of Nerve Injury-induced Protein 1 in Prostate Cancer | OMICS International | Abstract

Journal of Prostate Cancer
Open Access

Like us on:

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations
700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Research Article

Genetic Polymorphism of Nerve Injury-induced Protein 1 in Prostate Cancer

Jae Young Joung1, Sang Jin Lee2, Aesun Shin3, Weon Seo Park1, Jeong Eun Kim1, Ho Kyung Seo1, Jinsoo Chung1, Jung-Ah Hwang4, Seung-Hyun Hong4, Jeongseon Kim5, Kang Hyun Lee1 and Yeon-Su Lee4*

1Center for Prostate Cancer, National Cancer Center, Goyang, Korea

2Genitourinary Cancer Branch, National Cancer Center, Goyang, Korea

3Department of Preventive Medicine, Seoul National University College of Medicine, Seoul, Korea

4Functional Genomics Branch, National Cancer Center, Goyang, Korea

5Molecular Epidemiology Branch, National Cancer Center, Goyang, Korea

*Corresponding Author:
Yeon-Su Lee, Ph.D
Cancer Genomics Branch
National Cancer Center, Korea
Tel: +82-31-920-2550
E-mail: [email protected]

Received Date: February 17, 2016; Accepted Date: February 24, 2016; Published Date: March 02, 2016

Citation: Joung JY, Lee SJ, Shin A, Park WS, Kim JE, et al. (2016) Genetic Polymorphism of Nerve Injury-induced Protein 1 in Prostate Cancer. JPS Open Access 1:103. doi:10.4172/jps.1000103

Copyright: © 2016 Joung JY, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.


Objective: To investigate the association of genetic variants of nerve injury-induced protein 1 (NINJ1) with risk of prostate cancer in Korean men, we performed this association study using single nucleotide polymorphism (SNP).

Materials and methods: We enrolled 383 patients with prostate cancer and 373 healthy controls. Twentysix candidate SNPs of the NINJ1 gene were selected for genotype analysis. The distribution of each genotype and haplotype was analyzed, and their association with the incidence of prostate cancer was evaluated.

Results: None of the SNPs and haplotypes showed significant associations with prostate cancer risk in our subjects. In relation to the genotype frequency, 14 out of the 24 characterized SNPs revealed monomorphic features in cases and controls.

Conclusions: Although no association was observed between SNPs of the NINJ1 gene and prostate cancer risk, this study is meaningful because it is the first report to investigate the genetic epidemiology of the NINJ1 gene in relation to the development of prostate cancer. In addition, we observed monomorphic features of several SNPs of the NINJ1 gene in Korean men,and this finding was similar to that observed in Chinese and Japanese men based on the review of SNP database.


Peer Reviewed Journals
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2018-19
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri & Aquaculture Journals

Dr. Krish

[email protected]

+1-702-714-7001Extn: 9040

Biochemistry Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Business & Management Journals


[email protected]

1-702-714-7001Extn: 9042

Chemistry Journals

Gabriel Shaw

[email protected]

1-702-714-7001Extn: 9040

Clinical Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Engineering Journals

James Franklin

[email protected]

1-702-714-7001Extn: 9042

Food & Nutrition Journals

Katie Wilson

[email protected]

1-702-714-7001Extn: 9042

General Science

Andrea Jason

[email protected]

1-702-714-7001Extn: 9043

Genetics & Molecular Biology Journals

Anna Melissa

[email protected]

1-702-714-7001Extn: 9006

Immunology & Microbiology Journals

David Gorantl

[email protected]

1-702-714-7001Extn: 9014

Materials Science Journals

Rachle Green

[email protected]

1-702-714-7001Extn: 9039

Nursing & Health Care Journals

Stephanie Skinner

[email protected]

1-702-714-7001Extn: 9039

Medical Journals

Nimmi Anna

[email protected]

1-702-714-7001Extn: 9038

Neuroscience & Psychology Journals

Nathan T

[email protected]

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

Ann Jose

[email protected]

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

[email protected]

1-702-714-7001Extn: 9042

© 2008- 2018 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
Leave Your Message 24x7