Genotoxicity: Modern Instrumental Approaches for its Control in Environmental Objects
National University of Life and Environmental Sciences of Ukraine, Heroyiv Oborony St, Ukraine
- *Corresponding Author:
- Starodub NF
National University of Life and
Environmental Sciences of Ukraine
Heroyiv Oborony St, 15
Tel: +380 44 527 824
E-mail: [email protected]
Received Date: April 07, 2015 Accepted Date: June 12, 2015 Published Date: June 22, 2015
Citation: Starodub NF (2015) Genotoxicity: Modern Instrumental Approaches for its Control in Environmental Objects. J Biosens Bioelectron 6:169. doi: 10.4172/2155-6210.1000169
Copyright: © 2015 Starodub NF. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
The special attention is given to methods for control of genotoxicity. Among them, the detailed analysis is given that approaches which are based on the traditional molecular genetics tests, common instrumental systems and a modern biosensor devices. It is provided as general characteristics of the developed widely dispersed, most applicable in the practice approaches and detailed description of the basic principles of their functioning. The last a specially concerns instrumental analytical methods and, in particular, cell biosensors considering the possible type of the transducers, types of cells as sensitive structures, their integration in sensor elements and way of specific signal registration. In general it is analysed sensitivity and field of application of the existed approaches for the control of total toxicity and genotoxicity.