alexa Glycosylated Hemoglobin in Diabetic Foot and its Correl
ISSN: 2155-6156

Journal of Diabetes & Metabolism
Open Access

Like us on:
OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Research Article

Glycosylated Hemoglobin in Diabetic Foot and its Correlation with Clinical Variables in a North Indian Tertiary Care Hospital

Mohammad Zubair1*, Abida Malik2 and Jamal Ahmad1

1Rajiv Gandhi Centre for Diabetes and Endocrinology, Faculty of Medicine, J.N. Medical College, Aligarh Muslim University, Aligarh 202002, India

2Department of Microbiology, Faculty of Medicine, J.N. Medical College,, Aligarh Muslim University, Aligarh 202002, India

Corresponding Author:
Mohammad Zubair
Rajiv Gandhi Centre for Diabetes and Endocrinology
Faculty of Medicine, J.N. Medical College
Aligarh Muslim University, Aligarh 202002, India
Tel: 0091-9410200162
E-mail: [email protected]

Received Date: May 07, 2015; Accepted Date: May 28, 2015; Published Date: June 03, 2015

Citation: Zubair M, Malik A, Ahmad J (2015) Glycosylated Hemoglobin in Diabetic Foot and its Correlation with Clinical Variables in a North Indian Tertiary Care Hospital. J Diabetes Metab 6:571. doi:10.4172/2155-6156.1000571

Copyright: © 2015 Zubair M, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

 

Abstract

HbA1c reflects glycemia over 2-3 months and is the standard measure used to monitor glycemia in diabetic patients, but studies have not shown an association of HbA1c with DFU. We hypothesized that elevated HbA1c would be most associated with extremity of DFU/DFI. To test this hypothesis we conducted a prospective study of 161 DFU individuals treated at the R G Centre for Diabetes & Endocrinology, AMU. 64.8% were males and the 37.0% had ulcer >1 month. The majority of ulcer was neuropathic (50%) and amputation was done in 28.4%. HbA1c >6.5% were significantly associated with Wagner grades, UTG, BMI, retinopathy, nephropathy, hypertension, neuropathy and smoking. A significant correlation was found between UTG (r=-0.219, p=0.005), ulcer duration >1 month (r=-0.233, p=0.002), BMI (r=0.154, p=0.05), ESR (r=-0.169, p=0.031), Neuropathy (r=-0.007, p=0.048), nephropathy (r=-0.165, p=0.036), hypertension (r=0.207, p=0.007), retinopathy (r= 0.167, p=0.037) and smoking (r=0.164, p=0.034)with HbA1c >6.5%. The diabetic patients with A1c>6.5% showed a high risk of ulcer development in their foot. A significant correlation was observed with the clinical variables (ulcer duration >1 month, BMI, ESR, Neuropathy, nephropathy, hypertension, retinopathy and smoking with A1c>6.5% which is independent of concomitant infections in DFU patients.

Keywords

Share This Page

Additional Info

Loading
Loading Please wait..
 
Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

 
© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
adwords