alexa Gonadotropin Ovulation Induction (OI) and Intrauterine Insemination IUI): An Outdated Therapy
ISSN: 2375-4508

Journal of Fertilization: In Vitro - IVF-Worldwide, Reproductive Medicine, Genetics & Stem Cell Biology
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Gonadotropin Ovulation Induction (OI) and Intrauterine Insemination IUI): An Outdated Therapy

Paul R Brezina*
Department of Obstetrics and Gynecology, Vanderbilt University Medical Center, B-1100 Medical Center North Nashville, Tennessee 37232, USA
Corresponding Author : Paul R Brezina, MD, MBA
Clinical Assistant Professor
Department of Obstetrics and Gynecology
Vanderbilt University Medical Center
B-1100 Medical Center North Nashville
Tennessee 37232, United States
Tel: 901-747-2227
Fax: 901-747-4449
Received January 05, 2016; Accepted January 05, 2016; Published January 12, 2016
Citation: Brezina PR (2016) Gonadotropin Ovulation Induction (OI) and Intrauterine Insemination (IUI): An Outdated Therapy. J Fertil In Vitro IVF Worldw Reprod Med Genet Stem Cell Biol 4: e122. doi:10.4172/2375-4508.1000e122
Copyright: © 2016 Brezina PR. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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Traditionally, ovulation induction (OI) with intrauterine insemination (IUI) has been a strategy used to maximize pregnancy outcomes in patients attempting pregnancy. A common pattern of performing OI/IUI historically has been to begin OI using oral medications, such as Clomiphene Citrate or Letrozole, and then escalating medical management to include injectable Gonadotropins such as follicle stimulating hormone (FSH). However, current medical literature shows Gonadotropin IUI to be associated inferior to other available fertility therapies in terms of both medical risks and cost effectiveness. Therefore, Gonadotropin IUI is now thought to be a suboptimal intervention for many patients. Based on current medical literature, the role of Gonadotropin IUI is likely to continually decline in the future. This trend will benefit patients by decreasing medical risks and increasing the cost effectiveness of fertility treatments.

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