alexa Green Synthesis of Silver Nanoparticles from Glycyrrhiza glabra Root Extract for the Treatment of Gastric Ulcer
ISSN: 2329-6631

Journal of Developing Drugs
Open Access

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Research Article

Green Synthesis of Silver Nanoparticles from Glycyrrhiza glabra Root Extract for the Treatment of Gastric Ulcer

Sreelakshmy V1*, Deepa MK2* and Mridula P1

1Department of Pharmaceutics, Nehru College of Pharmacy, Pampady, Thiruvilwamala, Thrissur, Kerala, India

2Department of Pharmaceutics, Ahalia School of Pharmacy, Kozhipara, Palakkad,Kerala, India

*Corresponding Author:
Sreelakshmy V
PG Student, Department of Pharmaceutics
Nehru College of Pharmacy
Pampady, Thiruvilwamala
Thrissur, Kerala, India
E-mail:
[email protected]

Deepa MK
Associate Professor
Department of Pharmaceutics
Ahalia School of Pharmacy
Kozhipara, Palakkad
Kerala, India
Email: [email protected]

Received date: March 12, 2016; Accepted date: March 28, 2016; Published date: April 09, 2016

Citation: Sreelakshmy V, Deepa MK, Mridula P (2016) Green Synthesis of Silver Nanoparticles from Glycyrrhiza glabra Root Extract for the Treatment of Gastric Ulcer. J Develop Drugs 5:152. doi:10.4172/2329-6631.1000152

Copyright: © 2016 Sreelakshmy V, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

 

Abstract

Glycyrrhiza glabra is a traditional herb which grows in various parts of the world, which have been used for the treatment of various diseases like gastric ulcer. Many reports have been published about the biogenesis of silver nanoparticles using Glycyrrhiza glabra, but green synthesized silver nanoparticles from Glycyrrhiza glabra has not yet been investigate the in-vitro anti-ulcer activity against H. pylori. In the present study was aimed to investigate the in-vitro anti-ulcer activity of green-synthesised silver nanoparticles (AgNPs) from Glycyrrhiza glabra root extract. The green synthesized of silver nanoparticles were characterized by UV-Visible Spectroscopy, X-ray diffraction (XRD), TEM, and FT-IR Analysis. UV-VIS Spectral analysis of the green synthesised nanoparticles was observed a sharp peak at 404 nm indicates the formation of silver nanoparticles. We successfully synthesized uniformly dispersed silver nanoparticles with a uniform size and shape in the range of 7 nm to 45 nm with an average size of 19 nm. The crystalline natures of Ag nanoparticles were confirmed from the XRD analysis. FTIR analysis was carried out to identify the possible biomolecules in Glycyrrhiza glabra root responsible for capping leading to efficient stabilization of the silver nanoparticles. The in-vitro antiulcer activities of synthesized silver nanoparticles were studied by Agar disc diffusion method and Micro broth dilution method. In Agar disc diffusion method showed the activity against H. pylori at the concentration of 500 μg/ml, which exhibit the most potent concentration of silver nanoparticles of gastric Cytoprotective anti-ulcer. In micro broth dilution method, The Minimum Inhibitory Concentration (MIC) of silver nanoparticles by visual examination was found to be 250 μg/ml.

Keywords

Share This Page

Additional Info

Loading
Loading Please wait..
 
Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri, Food, Aqua and Veterinary Science Journals

Dr. Krish

[email protected]

1-702-714-7001 Extn: 9040

Clinical and Biochemistry Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Business & Management Journals

Ronald

[email protected]

1-702-714-7001Extn: 9042

Chemical Engineering and Chemistry Journals

Gabriel Shaw

[email protected]

1-702-714-7001 Extn: 9040

Earth & Environmental Sciences

Katie Wilson

[email protected]

1-702-714-7001Extn: 9042

Engineering Journals

James Franklin

[email protected]

1-702-714-7001Extn: 9042

General Science and Health care Journals

Andrea Jason

[email protected]

1-702-714-7001Extn: 9043

Genetics and Molecular Biology Journals

Anna Melissa

[email protected]

1-702-714-7001 Extn: 9006

Immunology & Microbiology Journals

David Gorantl

[email protected]

1-702-714-7001Extn: 9014

Informatics Journals

Stephanie Skinner

[email protected]

1-702-714-7001Extn: 9039

Material Sciences Journals

Rachle Green

[email protected]

1-702-714-7001Extn: 9039

Mathematics and Physics Journals

Jim Willison

[email protected]

1-702-714-7001 Extn: 9042

Medical Journals

Nimmi Anna

[email protected]

1-702-714-7001 Extn: 9038

Neuroscience & Psychology Journals

Nathan T

[email protected]

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

John Behannon

[email protected]

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

[email protected]

1-702-714-7001 Extn: 9042

 
© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
adwords