Hairy Cell Leukemia Associated with a Bone Marrow TuberculosisHarif M*
Mohammed VI University Hospital, University Cadi Ayyad, Marrakech, Morocco
- *Corresponding Author:
- Harif M
Mohammed VI University Hospital
University Cadi Ayyad, Marrakech, Morocco
E-mail: [email protected]
Received Date: September 04, 2015 Accepted Date: December 10, 2015 Published Date: December 16, 2015
Citation: Harif M (2015) Hairy Cell Leukemia Associated with a Bone Marrow Tuberculosis. J Cytol Histol 7:382. doi:10.4172/2157-7099.1000382
Copyright: © 2015 Harif M. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Hairy cell leukemia is a chronic B-cell lymphoid leukemia characterized by pancytopenia, splenomegaly, myelofibrosis and the presence in peripheral blood, bone marrow and spleen of atypical lymphoid cells with a hairy aspect and a particular immunophenotypic profil. The association HCL and tuberculosis has been established, but only few cases have been reported. We report a case of bone marrow tuberculosis with concomitant HCL. Initially, the histopathology of bone marrow led to a diagnosis of tuberculosis and myelofibrosis, without sufficient evidence for HCL. The anti-bacillary treatment was then started. Three months later, aspiration, biopsy and immunophenotyping of bone marrow were performed, a lymphoid population evoking hairy cells, was found. The patient received chemotherapy based pentostatin. The outcome was favorable.