Healthcare Functions of Cordyceps cicadaeJui-Hsia Hsu1, Bo-Yi Jhou1, Shu-Hsing Yeh1, Yen-lien Chen1 and Chin-Chu Chen2,3,4*
- *Corresponding Author:
- Chin-Chu Chen
PhD,. NO.60, Sec. 3, Longgang Rd.
Zhongli Dist., Taoyuan City 320, Taiwan (ROC.)
E-mail: [email protected]
Received date: October 20, 2015; Accepted date: November 05, 2015; Published date: November 09, 2015
Citation: Hsu JH, Jhou BY, Yeh SH, Chen Yl, Chen CC (2015) Healthcare Functions of Cordyceps cicadae. J Nutr Food Sci 5:432. doi: 10.4172/2155-9600.1000432
Copyright: © 2015 Hsu JH, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Cordyceps cicadae (C. cicadae) is one of the most valued traditional Chinese medicines (TCM) and have been used for about 1,600 years in China. Both TCM works and modern pharmacological studies indicate that C. cicadae exhibits a variety of biological functions, including vision improvement and protection of renal function. There are at least five active ingredients in C. cicadae, suggesting that further exploration on bioactive metabolites of C. cicadae is expected to expand for its application scope and better exert its healthcare efficacy. Because of the shortage of wild C. cicadae, artificially cultivated is an ideal substitute. The methods we developed include fruiting body production based on wild culture matrix, cultivation based on infected nymphs, liquid fermentation of mycelium. Safety evaluation of the artificially cultivated C. cicadae is important in development of C. cicadae-related product. No toxic effect was observed in the acute toxicity test (piglet), 3 different test systems of genotoxicity test, a 90- day oral toxicity test (rats), as well as teratogenicity test of C. cicadae mycelium. C. cicadae possesses multiple pharmacological activities that offers several featured advantages such as low toxicity, low price and easy availability of raw materials from artificial cultivation, paving a broad way for functional products and supplements incorporating healthcare foods, cosmetics, biological agriculture, and pharmaceuticals.