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Health-Related Quality of Life is Associated with Hemoglobin Level in Children with Sickle Cell Anemia | OMICS International | Abstract
ISSN: 2155-9864

Journal of Blood Disorders & Transfusion
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Research Article

Health-Related Quality of Life is Associated with Hemoglobin Level in Children with Sickle Cell Anemia

Ruth Williams-Hooker1,2*, Stacie Olivi1, Matthew P Smeltzer3 and Winfred C Wang4

1Clinical Nutrition Services, St. Jude Children’s Research Hospital, 262 Danny Thomas Place, Memphis, TN 38105-3678, USA

2The University of Memphis, Department of Health and Sports Science, Memphis TN 38152, USA

3Department of Biostatistics, St. Jude Children’s Research Hospital, 262 Danny Thomas Place, Memphis, TN 38105-3678, USA

4Department of Hematology, St. Jude Children’s Research Hospital, 262 Danny Thomas Place, Memphis, TN 38105-3678, USA

*Corresponding Author:
Ruth Williams Hooker, MS, RD, EdD
Assistant Professor and Director
Clinical Nutrition Masters/Internship Program
Health and Sport Sciences
The University of Memphis,161 Field House,Memphis,TN 38152,USA
Tel: 901-678-3108
Fax:
901-678-3591
E-mail: [email protected]

Received date: July 17, 2012; Accepted date: August 28, 2012; Published date: August 30, 2012

Citation: Williams-Hooker R, Olivi S, Smeltzer MP, Wang WC (2012) Health-Related Quality of Life is Associated with Hemoglobin Level in Children with Sickle Cell Anemia. J Blood Disord Transfus 3:129. doi: 10.4172/2155-9864.1000129

Copyright: © 2012 Williams-Hooker R, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Abstract

Purpose: Pediatric health quality of life (HQOL) refers to a child’s physical, emotional, and social well being. HQOL is often compromised in persons with sickle cell anemia (SCA). The purpose of this study was to compare HQOL with hemoglobin in children with SCA. Methods: In a pilot study looking at energy expenditure in children with SCA, we measured subjects’ QOL using the PedsQL survey and compared it to their hemoglobin (Hb) levels at baseline. Results: Twenty-five subjects, all with HbSS, completed the instrument. Their mean age (standard deviation) was 11.4 (3.25) years and 52% were male. Their mean Hb level was 8.4 (1.2) g/dL. Higher scores in social functioning (R=0.63, p=0.0001) and school functioning (R=0.40, p=0.05) were significantly associated with higher Hb levels. Conclusions: We conclude that Hb level is related to HQOL and that treatments aimed at improving Hb may help to improve overall HQOL.

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