alexa Helicobacter pylori and Perinatal Pathologies: Pathogen Transmission During Childbirth?
ISSN: 0974-8369

Biology and Medicine
Open Access

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Review Article

Helicobacter pylori and Perinatal Pathologies: Pathogen Transmission During Childbirth?

Marcela Espinoza Monje1, Ana Marín Vega1, Lillian Matamala Valdés2 and Apolinaria García Cancino1*

1Department of Microbiology, Faculty of Biological Sciences, University of Concepcion, Concepcion, Chile

2Department of Obstetrics and Childcare, Faculty of Medicine, University of Concepcion, Concepcion, Chile

Corresponding Author:
Dr. Apolinaria García Cancino
Department of Microbiology, Faculty of Biological Sciences
University of Concepcion, PO Box 160C, Concepcion, Chile
Tel: 56- 41-2204144/56-41-2204118
E-mail: [email protected]

Received Date: June 15, 2016; Accepted Date: July 15, 2016; Published Date: July 22, 2016

Citation: Monje ME, Vega AM, Valdés LM, Cancino AG (2016) Helicobacter pylori and Perinatal Pathologies: Pathogen Transmission During Childbirth? . Biol Med (Aligarh) 8:313. doi:10.4172/0974-8369.1000313

Copyright: © 2016 Cancinoa AG, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution and reproduction in any medium, provided the original author and source are credited.



Perinatal pathologies are diseases that show up during pregnancy until after the boy or girl´s birth, up to 28 days of life approximately. Helicobacter pylori infection is more frequent during pregnancy because in this period there is a decrease of the immune response mediated by cytotoxic cells with preservation of innate humoral immunity that causes bacterial activation and consequently a negative impact both for the mother´s as well as for the fetus´s health. Some of the perinatal pathologies related to this particular infection are: hyperemesis gravidarum, iron-deficiency anemia, restriction of intrauterine growth, spontaneous abortion and preeclampsia. The purpose of this review is to analyze pathologies linked to Helicobacter pylori infection during the pregnancy and find out if this pathogen can be transmitted from the mother to the child. It is concluded that the presence of Helicobacter pylori is considered a risk factor for each one of the aforementioned perinatal pathologies. However, this subject still needs further study, altogether with the potential impact of the pre-conception research and Helicobacter pylori infection eradication during this particular period. Vaginal yeast would be the main reservoir of this microorganism and it would enable its transmission to new-born babies.


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