Helicobacter pylori Infections in Children of a Rural Community
- *Corresponding Author:
- Abdel Razak
Department of Pediatrics, Al-Azhar University, Egypt
E-mail: [email protected]
Received Date: February 13, 2014; Accepted Date: April 01, 2014; Published Date: April 03, 2014
Citation: Abdel Razak and Mahmoud Saad Ragab (2014) Helicobacter pylori Infections in Children of a Rural Community. J Bacteriol Parasitol 5:185. doi: 10.4172/2155-9597.1000185
Copyright: © 2014 Razak A, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Design: Case control study.
Setting: Local tertiary centre in Gizan District, Saudi Arabia.
Participants: In this case control study the number of patients (H. pylori positive) were 120 (52.5% Boys) and the control group patients (H. pylori negative) were 100 cases, aged 7-12 years old (mean 9.9 ± 3 years). The patient and control groups were matched for age, race and sex. All cases were clinically examined for weight, height, iron deficiency (sideropenic) anemia and gastrointestinal (GIT) symptoms.
Main Exposures: H. pylori infections were defined by positive H. pylori stool antigen test and Serum IgG or Urea Breath Tests.
Main Outcome Measures: All cases were assessed for weight, height, iron deficiency (sideropenic) anemia and GIT symptoms.
Results: Recurrent abdominal pain, anorexia and recurrent vomiting were 81(67.5%), 24 (20%) and 15(12.5) % respectively in H. pylori infected patients, compared to 28 (28%), 8 (8%) and 4 (4%) in control group. Weight and height were (20.4 ± 1 kg and 128.1 ± 1 cm) in patients compared to (25.6 ± 1.7 kg and 133.8 ± 2 cm) in control cases. Sideropenic anemia was 36.7 % in patients compared to 15% in control.
Conclusion: Our findings suggest that Pediatric H. pylori infection not only present with recurrent abdominal pain, anorexia and recurrent vomiting, but also negatively affects the growth of children in various modalities; in particular weight, height and the progressive incidence of iron deficiency anemia.