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ISSN: 2161-1041

Hereditary Genetics: Current Research
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Review Article

Hereditary Cancer Risk Assessment: How Best can we Achieve it?

Israel Gomy* and Maria Del Pilar Estevez Diz

Sao Paulo Cancer Institute, Sao Paulo, Brazil

*Corresponding Author:
Israel Gomy, MD, PhD
Cancer geneticist
Sao Paulo Cancer Institute
Sao Paulo, Brazil
Tel: +55 11 29250500
E-mail: [email protected]

Received Date: April 26, 2013; Accepted Date: May 06, 2013; Published Date: May 18, 2013

Citation: Gomy I (2013) Hereditary Cancer Risk Assessment: How Best can we Achieve it? Genetics S2:003. doi: 10.4172/2161-1041.S2-003

Copyright: © 2013 Gomy I. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Abstract

Hereditary cancer risk assessment (HCRA) is a multidisciplinary process of estimating probabilities of germline mutations in cancer susceptibility genes and assessing empiric risks of cancer, based on personal and family histories. It includes genetic testing and management of at-risk individuals so that they can make informed choices about cancer screening, surgical and chemo preventive options, as well as genetically targeted cancer therapies. Providing patients with pre- and post-test genetic counseling may help them to get better informed decision making.Following individuals at increased risk with surveillance protocols, reassuring those at low risk, and referring those at high risk of a hereditary cancer to a cancer genetics center with outpatient clinics may be the best suitable approach to HCRA.

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