High Rates of Fatality Due to AIDS without Universal HIV Testing
- *Corresponding Author:
- Fabiola Martin
Senior Clinical Lecturer in HIV Medicine
Centre for Immunology and Infection
University of York, Wentworth Way
York, YO10 5DD, UK
Tel: 01904 328907
Fax: 01904 328844
E-mail: [email protected]
Received Date: December 20, 2013; Accepted Date: February 26, 2014; Published Date: March 10, 2014
Citation: Bassi SS, Martin Bland J, Martin F (2014) High Rates of Fatality Due to AIDS without Universal HIV Testing. J AIDS Clin Res 5:291. doi:10.4172/2155-6113.1000291
Copyright: © 2014 Bassi SS, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
We audited the cause of death and surrogate markers of HIV patients living in a HIV low prevalence area of the UK. Fatality rates from 2001-2010 were compared to two high prevalence areas. 16/104 newly diagnosed patients died. The median time from diagnosis to death was 4.2 years (<1month-18 years): 6 (38%) died <12 months of diagnosis, 3 (19%) within 5 years, seven (44%) >10 years later; twelve (75%) were male, twelve (75%) Caucasian, eight (50%) were infected through heterosexual intercourse; median CD4 count was 44 cells/microL (range 2-475). Twelve (75%) patients died of AIDS, 4 (25%) of Pneumocystis jerovecii pneumonia. The observed case-fatality rate was 2.3 (95% CI 1.4-3.9) fold higher in this low prevalence area compared to high prevalence areas (p<0.001), where universal HIV testing is promoted. It is possible that an early detection of HIV through universal instead of targeted HIV testing in sexually active adults in all areas of the UK could lead to a reduction of premature death due to AIDS.