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ISSN 2155-6113

Journal of AIDS & Clinical Research
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Research Article

HIV and Periodontal Disease: Redemption or Resurrection

Ashita .S. Uppoor1* and Dilip .G. Nayak2

1Department of Periodontics, Manipal College of Dental Sciences, Mangalore, Karnataka, India

2Professor & Associate Dean, Manipal College of Dental Sciences, Mangalore, Karnataka, India

*Corresponding Author:
Ashita S Uppoor, MDS
Professor & Head, Department of Periodontics
Manipal College of Dental Sciences
Mangalore, Karnataka, India
Tel: 00919880038082
E-mail: [email protected]

Received Date: August 11, 2012; Accepted Date: September 17, 2012; Published Date: September 19, 2012

Citation: Uppoor AS, Nayak DG (2012) HIV and Periodontal Disease: Redemption or Resurrection. J AIDS Clinic Res 3:168. doi: 10.4172/2155-6113.1000168

Copyright: © 2012 Uppoor AS, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Abstract

Human immunodeficiency virus (HIV) infection, a major medical crisis that has hit families, communities & nations across the world, remains a major health concern of unprecedented dimension. Mounting evidence suggests that co-infections and inflammation may result in re-activation of latent virus and blunt the success of Highly Active Anti-retroviral Therapy (HAART). Periodontal diseases are chronic multibacterial infections that can result in significant bacterial & inflammatory load in the body and HIV infection has been found to be associated with various forms of periodontal diseases. Besides Immune Reconstitution Inflammatory Syndrome (IRIS), following HAART, may also lead to increased frequency of periodontal disease among these patients. If co-infections & inflammation can increase the risk of HIV reactivation, can periodontitis in an HIV infected individual lead to HIV re-activation. This question remains unanswered, but initial evidence suggests a probable role of periodontitis in HIV re-activation. The clinical implication of such a role is that, periodontitis being most often preventable and definitely treatable, every attempt should be made to prevent and promptly treat this disease in individuals with HIV infection.

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