alexa Hoffmann ’ s Syndrome a Presenting Manifestation of Hypothyroidism
ISSN: 2165-7920

Journal of Clinical Case Reports
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Case Report

Hoffmann ’ s Syndrome a Presenting Manifestation of Hypothyroidism

Amal Alkhotani*
Consultant Neurology, King Abdulla Medical City, Saudi Arabia
Corresponding Author : Amal Alkhotani, MBBCH
Assistant professor
Consultant Neurology, Umm AlQura University
King Abdulla Medical City, 3790 wali alahad street
Makkah, Saudi Arabia
Tel: 966569385387
Fax: 96625323218
E-mail: [email protected]
Received March 22, 2013; Accepted May 13, 2013; Published May 15, 2013
Citation: Alkhotani A (2013) Hoffmann’s Syndrome a Presenting Manifestation of Hypothyroidism. J Clin Case Rep 3:279. doi:10.4172/2165-7920.1000279
Copyright: © 2013 Alkhotani A. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
 

Abstract

Hypothyrodisim associated with different neuromuscular manifestations. Rarely patient with hypothyroidism may develop muscular pseudohypertrophy a condition called Hoffmann’s syndrome in adults. We report a patient present mainly with myelgia, cramps, calf pseudohypertrophy and persistently elevated Creatine Kinase (CK) with absence of other systemic symptoms of hypothyroidism. His laboratory works revealed severe hypothyroidism. Treatment with L-thyroxine resulted into disappearance of symptoms, normalization of CK and return of calf size to normal. Hypothyrodism should be considered when evaluating patients with neuromuscular complaints even in absence of systemic symptoms.

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