alexa How Nanotechnology can Really Improve the Future of Orthopedic Implants and Scaffolds for Bone and Cartilage Defects
ISSN: 2155-983X

Journal of Nanomedicine & Biotherapeutic Discovery
Open Access

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Review Article

How Nanotechnology can Really Improve the Future of Orthopedic Implants and Scaffolds for Bone and Cartilage Defects

Parchi PD1*, Vittorio O2, Andreani L1, Piolanti N1, Cirillo G3,4, Iemma F3, Hampel S4 and Lisanti M1

11st Orthopedic Division, Department of Translational Research and New Technologies in Medicine, University of Pisa, via Paradisa 2 56124 Pisa (PI), Italy

2Australian Centre for Nanomedicine, University of New South Wales, 2031 Australia

3Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036 Arcavacata di Rende (CS), Italy

4Leibniz Institute for Solid State and Materials Research Dresden, PF 270116, D-01171 Dresden, Germany

*Corresponding Author:
Parchi Paolo Domenico
Assistant Professor
1st Orthopedic Division
Department of Translational Research and New Technologies
in Medicine, University of Pisa
via Paradisa 2 56124 Pisa (PI), Italy
Tel: 00393470781567
E-mail: [email protected]

Received date: July 06, 2013; Accepted date: August 19, 2013; Published date: August 22, 2013

Citation: Parchi PD, Vittorio O, Andreani L, Piolanti N, Cirillo G, et al. (2013) How Nanotechnology can Really Improve the Future of Orthopedic Implants and Scaffolds for Bone and Cartilage Defects. J Nanomedine Biotherapeutic Discov 3:114. doi: 10.4172/2155-983X.1000114

Copyright: © 2013 Parchi PD, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.



Theosteointegrat ion of the orthopaedic implants could improve the biocompatibility and the life span of the implants. The ideal implants should be made by materials easily colonized by bone-forming cells (osteoblasts), which can synthesize new bone matrix. Some implant materials are not often compatible with osteoblasts, but rather they promote the formation of soft connective tissue. There are a number of important reasons to explore the potential for the application of nanomaterials in orthopedic surgery. The use of nanotechnology has been tested on a wide range of materials (such as metals, ceramics, polymers, and composites), where either nanostructured surface features or constituent nanomaterials (including grains, fibers, or particles with at least one dimension from 1 to 100 nm) have been utilized. These nanomaterials have demonstrated superior properties compared with their conventional (or micron structured) counterparts, due to their distinctive nanoscale features and the novel physical properties that ensue. Aim of this paper is to explore how nanotechnology can really improve the future of orthopedic implants and scaffolds for bone and cartilage defects. Here we are showing the most relevant works about the use of nanotechnologies for the treatment of osteocondral defects.


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