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ISSN: 2165-7920

Journal of Clinical Case Reports
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Case Report

Huge Localized Amyloidosis of the Sinonasal Cavity: A Rare Case Report

Kunihiro Nishimura1*, Shuho Tanaka2, Yasuhiko Takahashi3, Yasue Uchida1, Tooru Tanigawa1, Hiromi Ueda1 and Tetsuya Ogawa1

1Department of Otorhinolaryngology, Aichi Medical University School of Medicine, Japan

2Department of Otolaryngology, Faculty of Medicine, University of Tsukuba, Japan

3Department of Oculoplastic, Orbital, and Lacrimal Surgery, Aichi Medical University Hospital School of Medicine, Japan

Corresponding Author:
Kunihiro Nishimura
Department of Otorhinolaryngology Aichi
Medical University School of Medicine, Japan
Tel:
+81561-62-3311
E-mail: [email protected]

Received April 26, 2016; Accepted May 23, 2016; Published May 27, 2016

Citation: Nishimura K, Tanaka S, Takahashi Y, Uchida Y, Tanigawa T, et al. (2016) Huge Localized Amyloidosis of the Sinonasal Cavity: A Rare Case Report. J Clin Case Rep 6: 797. doi:10.4172/2165-7920.1000797

Copyright: © 2016 Nishimura K, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Abstract

Background: Amyloidosis is the general term for deposition of fibrous abnormal protein aggregates (amyloid) in organs or tissues that leads to dysfunction of the affected organs. Treatment and follow-up of localized amyloidosis are particularly difficult because its pathogenesis is still unclear. Localized amyloidosis of the head and neck is rare and that of the nose is rarer still. Here, we report a case of localized amyloidosis of the nasal cavity, which affected an area larger than those in previous reports. Case presentation: A 60-year-old woman presented with the chief complaints of headache, proptosis and nasal congestion. There was a lack of response to chemotherapy and endoscopic sinus surgery was performed. As of 18 months after surgery, subjective symptoms have been alleviated and are consistent with the objective findings. There have been no signs of recurrence. Conclusions: Cases of localized amyloidosis of the nasal cavity are rare, and standard treatment has not yet been established. In this case, proactive surgical intervention was successful for this condition.

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