alexa "Hungry Bone" Syndrome after Parathyroidectomy: Up-To-D
[Jurnalul de Chirurgie]
ISSN: 1584-9341

Journal of Surgery
Open Access

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Review Article

"Hungry Bone" Syndrome after Parathyroidectomy: Up-To-Date

Daniela Tatiana Sala1, Ioan Tilea2*, Ioana Pantea1, Ionela Pascanu3, Nutu Vlad4 and Radu Mircea Neagoe1

12nd Unit of Surgery, Department of Surgery, University of Medicine and Pharmacy Targu Mures, Romania

2Department of Cardiac Rehabilitation, University of Medicine and Pharmacy Targu Mures, Romania

3Department of Endocrinology, University of Medicine and Pharmacy Targu Mures, Romania

4Department of Surgery, University of Medicine and Pharmacy “Gr.T. Popa”, Iasi, Romania

*Corresponding Author:
Ioan Tilea
Associated Professor of Internal Medicine
Department of Cardiac Rehabilitation
Targu Mures Emergency Clinical County Hospital
Targu Mures, Romania
Tel: +40(0) 748-16-45-85
Fax: +40 (0) 265.21.10.11
E-mail: [email protected]

Received Date: February 15, 2015 Accepted Date: July 10, 2015 Published Date: July 17, 2015

Citation: Sala DT, Tilea I, Pantea I, Pascanu I, Vlad N, et al. “Hungry Bone” Syndrome after Parathyroidectomy: Up-To-Date. Journal of Surgery [Jurnalul de chirurgie]. 2015; 11(4): 133-136 DOI:10.7438/1584-9341-11-4-3 [article in Romanian]

Copyright: © 2015 Sala DT, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

 

Abstract

The hungry bone syndrome is considered in literature as being a complication following parathyroidectomy and it refers to the rapidly installed, severe, prolonged, and in most cases clinically manifested hypocalcaemia, which is sometimes accompanied by hypophosphatemia and hypomagnesemia. It appears due to the rapid demineralization of the dystrophic bone as a result of the sudden drop in the seric level of the parathyroid hormone. The prevalence of this complication is reported in literature with different variations, the number reported ranging from 4-95% depending on the type of affection - i.e. primary hyperparathyroidism or renal secondary hyperparathyroidism, but also on the geographical areas where the respective reports have been filled. The high preoperatory level of calcaemia, seric parathyroid hormone and alkalyne phophatase correlate statistically with the risk of postoperatory hungry bone syndrome appearance; the elderly patients present a higher risk for this complication, increasingly because this category of patients is oftenly associated with D hypovitaminosis and insufficient intake of nutritional calcium. The syndrome semiology is one of a hypocalcaemia and the curative treatment is initially a symptomatic one of fighting the severe postparathyroidectomy hypocalcaemia and only later a patogenic one, aiming to remineralize the distrofic bone. The purpose of this review is to describe the main epidemiologic, physiopathologic and clinical aspects of hungry bone syndrome but also of presenting prevention and treatment methods for this complication of parathyroidectomy.

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