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ISSN: 2167-0374

Journal of Defense Management
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Research Article

Hyperbaric Oxygen: Silver Bullet for Diabetic Foot Ulcers

Nasser Sharari1*, Mostafa Saleh2, Ahmed Morad3, Omar Khan1 and Yasser Al-Ghamady1
1Armed Forces Hospital Program-Jubail, Saudi Arabia
2Department of General Surgery, Benha University, Egypt
3Department of General Surgery, Ain Shams University, Egypt
*Corresponding Author : Nasser Sharari
Director of Surgery
Consultant GS Laparoscopic
Breast and Endocrine Surgery
King Abdulaziz Military Hospital Jubail
P.O. Box 413- Jubail 3195, Saudi Arabia
E-mail: [email protected]
Received May 04, 2013; Accepted May 11, 2013; Published May 17, 2013
Citation: Sharari N, Saleh M, Morad A, Khan O, Al-Ghamady Y (2013) Hyperbaric Oxygen: Silver Bullet for Diabetic Foot Ulcers. J Def Manag S3:008.doi: 10.4172/2167-0374.S3-008
Copyright: © 2013 Sharari N, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Abstract

Background: Hyperbaric Oxygen Therapy (HBOT) involves the administration of pure oxygen under high pressure conditions. HBOT is used as an adjuvant therapy for a variety of conditions; including chronic wounds, infections, stroke, tissue transplantation, anemia, cancer management, skin flaps & grafts, CO poisoning, air or gas embolism, decompression thickness, necrotizing fasciitis, crush injury, compartment syndrome, gas gangrene and autism.

Objective: This prospective study was designed to evaluate the efficacy of HBOT as adjuvant treatment for diabetic foot ulcers in comparison to the conventional treatment.

Patients and methods: This study comprised 82 diabetic patients, aged 38 to 72 years. Patients were randomized into two groups: Group A assigned to receive HBOT in combination with conventional wound care & group B received conventional wound care only for the treatment of diabetic foot ulcers. Outcomes were measured every week for 1st two months during the treatment period and then at three-month intervals for one year. Ulcers were graded using Wagner classification system. Both groups were compared as regards healing time, need of amputation, quality of life.

Results: The demographic characteristics of the 82 patients were 28 women (34%) and 54 men (65.9%), age range from 32 to 72 years. The median ulcer duration for both groups was 7.2 months, and the median ulcer area was 3.5 cm2. There was non-significant difference between both groups as regard demographic characteristics. Complete healing of the index ulcer was significantly faster in hyperbaric group 50% in comparison to 29% in group B. 2 major amputation were performed in HBOT group as compared to 3 cases in group B; all of them were Wagner grade IV. Five minor amputations were performed in each group during the 1st year of follow up. 63% of group A were satisfied as regard the management of their ulcers in comparison to 41% in group B.

Conclusion: This study supports the role of HBOT as an adjuvant in healing of diabetic foot ulcers & improving quality of life.

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