alexa Hypoglycemic Effect of Kyllinga Triceps in STZ Induced Diabetic Rats | OMICS International | Abstract
ISSN: 2155-6156

Journal of Diabetes & Metabolism
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Hypoglycemic Effect of Kyllinga Triceps in STZ Induced Diabetic Rats

Lal VK1, Gupta PP2 and Pandey Awanish3*

1Department of Pharmacy, SITM, Barabanki, UP, India

2B.R.D.Medical College, Gorakhpur, UP, India

3Research Scholar, UTU, Dehradun, Uttarkhand, India

*Corresponding Author:
Awanish Kumar Pandey
Research Scholar, UTU, Dehradun
Uttarkhand, India
E-mail: [email protected]

Received date: March 05, 2012; Accepted date: July 06, 2012; Published date: July 10, 2012

Citation: Lal VK, Gupta PP, Awanish P (2012) Hypoglycemic Effect of Kyllinga Triceps in STZ Induced Diabetic Rats. J Diabetes Metab 3: 204. doi:10.4172/2155-6156.1000204

Copyright: ©2012 Lal VK, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Abstract

Kyllinga triceps is an Indian medicinal plant demonstrated to exert multiple pharmacological effects. In light of traditional claim of the plant in treatment of diabetes, the present study was carried out to evaluate the hypoglycemic activity of the plant in Streptozotocin (STZ) induced diabetic rats. The diabetic rats were given Kyllinga triceps extract (KTE, 100mg/kg & 200mg/kg) and Glibenclamide (0.5mg/kg) for 28 days. The effects of both treatments on body weight and blood glucose were assessed. Both doses of extract and Glibenclamide showed significant hypoglycemic activity in acute and sub acute study. Body weight of extract and glibenclamide treated rats were maintained during the study period Where as body weight of untreated rats had gone down. The result obtained from the study scientifically proved the folkloric use of Kyllinga triceps as hypoglycemic agent. Thus the plant can be key contributor in treatment of Diabetes.
 

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