alexa Hypolipidemic Effect of Rice Fermented With Monascus Ruber CCT 1236 in Rabbits
ISSN: 2329-6836

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Research Article

Hypolipidemic Effect of Rice Fermented With Monascus Ruber CCT 1236 in Rabbits

Cristiane S Fonseca1, Larissa F Brito1*, Fabiano PPM1, Tânia T Oliveira2, Sérgio LPM2 and Jose H Queiroz1
1Department of Biochemistry and Molecular Biology, Federal University of Vicosa, Vicosa, 36570-000, Brazil
2Department of General Biology, Federal University of Vicosa, 36570-000 Brazil
Corresponding Author : Larissa F Brito
Department of Biochemistry and Molecular Biology
Federal University of Vicosa, 36570-000, Brazil
Tel: 3194195158
E-mail: [email protected]
Received June 28, 2014; Accepted September 05, 2014; Published September 08, 2014
Citation: Fonseca CS, Brito LF, Fabiano PPM, Oliveira TT, Sérgio LPM, et al. (2014) Hypolipidemic Effect of Rice Fermented With Monascus Ruber CCT 1236 in Rabbits. Nat Prod Chem Res 2:144. doi: 10.4172/2329-6836.1000144
Copyright: © 2014 Fonseca CS, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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Abstract

The objective of the present work was to evaluate the effects of rice fermented with Monascus ruber in the concentrations of rabbit serum lipids and the possible protective effects of fermented rice in injuries caused by hyperlipidemy. Blood samples were collected at the beginning of the experiment and during the interval of fifteen and thirty days to determine the levels of serum lipids. The fermented rice was effective in increasing the highdensity lipoprotein cholesterol (HDL-c) and reducing total cholesterol (TC), triglyceride (TG), low-density lipoprotein cholesterol (LDL-c) and very low-density lipoprotein cholesterol (VLDL-c). These effects were more significant when the diet containing 10% of fermented rice was used. It was found that the addition of fermented rice in the diets of the animals did not change the morphology of cells of the heart and prevented the formation of injuries resulting from hyperlipidemy.

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