alexa Hypotensive Anesthesia may Result in False Anemia and Increase Transfusion Requirements in Total Hip Arthroplasty
ISSN: 2155-6148

Journal of Anesthesia & Clinical Research
Open Access

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Research Article

Hypotensive Anesthesia may Result in False Anemia and Increase Transfusion Requirements in Total Hip Arthroplasty

Jad Bou Monsef and Friedrich Boettner*

Hospital for Special Surgery, New York, USA

*Corresponding Author:
Friedrich Boettner
Hospital for Special Surgery 535 East 70th Street, New York, NY 10021, USA
Tel: 212-774-2127
Fax: 212-774-2286
E-mail: [email protected]

Received date: June 17, 2014; Accepted date: July 29, 2014; Published date: July 31, 2014

Citation: Monsef JB, Boettner F (2014) Hypotensive Anesthesia may Result in False Anemia and Increase Transfusion Requirements in Total Hip Arthroplasty. J Anesth Clin Res 5:425. doi: 10.4172/2155-6148.1000425

Copyright: © 2014 Monsef JB, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.



Background: Deliberate hypotension under spinal or epidural anesthesia is a readily available and effective method to reduce intraoperative blood loss in total hip arthroplasty. However, induced hypotension has been shown to alter the physiologic handling of crystalloid solutions, with blood volume increasing in proportion to the drop in blood pressure. This study aims to investigate the effect of hemodilution secondary to hypotensive anesthesia and volume loading on postoperative hemoglobin levels.

Methods: 211 non-anemic adult patients who underwent primary total hip arthroplasty utilizing a minimal invasive posterior approach with hypotensive spinal-epidural anesthesia were evaluated retrospectively. The effect of fluid loading under hypotensive anesthesia was investigated by calculating the blood loss that corresponds to patients’ preoperative and postoperative hemoglobin levels, as well as calculating the hemoglobin levels expected for known volumes of blood loss.

Results: There was a large discrepancy between the calculated blood loss (1358 mL) and the actual measured blood loss (212 mL). Patients received an average of 4488 (SD 1209) mL of intravenous fluid within 24 hours of surgery. There was also a large difference between the calculated hemoglobin level based on the measured blood loss (13.6 g/dL) and the actual measured mean hemoglobin (10.8 g/dL).

Conclusion: Blood volume expansion and hemodilution with hypotensive epidural anesthesia leads to decreased hemoglobin levels in the early postoperative period and likely impacts on transfusion requirements. Hypotensive anesthesia might have a detrimental effect on transfusion requirements in procedures with relatively low blood loss.


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