Hypothyroidism Associated with Echocardiographic AbnormalitiesFaiza A Qari*
Professor, Department of Endocrinology, King Abdulaziz University, Jeddah, Saudi Arabia
- *Corresponding Author:
- Qari FA
Department of Endocrinology at King Abdulaziz University
P. Box 13043, 21943 Jeddah, Saudi Arabia
E mail : [email protected]
Received date: August 14, 2016; Accepted date: April 24, 2017; Published date: April 28, 2017
Citation: Qari FA (2017) Hypothyroidism Associated with Echocardiographic Abnormalities. Intern Med 7:237. doi:10.4172/2165-8048.1000237
Copyright: © 2017 Qari FA, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited
Objective: To evaluate the relationship between hypothyroidism and pericardial effusion, dilate cardiomyopathy and the LV ejection fraction (EF) through an echocardiographic scan.
Design: Retrospective study.
Settings: Single tertiary center, King Abdulaziz University Hospital, from January 2015 to January 2017.
Patients: 314 patients followed up for hypothyroidism.
Main outcome measures: Echocardiographic abnormalities.
Results: The average age of the subjected group was 57 which is significantly older than control group (P value=0.0001). In addition, the subjected group were treated with higher doses of amaidiorone than the control group which was quite a drastic difference (p value=0.037).
Similarly, such a drastic difference between both groups due to the low p value at <0.0001 - was also identified by how the ejection fraction (EF) of the subjected group was statically much lower than in the control group. The p values calculated in both cases were determined using the simple regression model.
It was also found that there was a negative to weak relationship as explained by the B coefficient (Regression Coefficient) amongst the cases/controls and the laboratory parameters. However, there was a significant correlation between EF and the FT3 level (r=0.818; p value=0.045).
Conclusion: The study showed the clear association of hypothyroidism with echocrsdiographic abnormalitis; lik cardiomyopathy and pericardial effusion. It was also deduced that patients suffering from severe hypothyroidism as well as cardiomyopathy had quite low levels of EF.