Hypovitaminosis D Status in Newly Diagnosed Cases of MS versus Control GroupMehdi Saeedan*, Yasamin Ghazvini Ko, Sudhir Kumar Palat Chirakkara, Shobhit Sinha and Ahmed Shatila
Neurology Department, Mafraq Hospital, Abu Dhabi, UAE
- *Corresponding Author:
- Saeedan M
Neurology Department, Mafraq Hospital
Abu Dhabi, UAE
E-mail: [email protected]
Received date: March 09, 2017; Accepted date: April 28, 2017; Published date: May 05, 2017
Citation: Saeedan M, Ko YG, Chirakkara SKP, Sinha S, Shatila A (2017) Hypovitaminosis D Status in Newly Diagnosed Cases of MS versus Control Group. J Mult Scler 4:199. doi:10.4172/2376-0389.1000199
Copyright: © 2017 Saeedan M, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution and reproduction in any medium, provided the original author and source are credited.
Background: Hypovitaminosis D is amongst those strongly suggested risk factors for multiple sclerosis (MS). Although the association of vitamin D deficiency with MS has been established in several studies in recent years, there are not many studies to assess and compare the degree of Hypovitaminosis D status of newly diagnosed patients with multiple sclerosis versus control group worldwide, especially in UAE. Objective: To compare and observe the state of Hypovitaminosis D in newly diagnosed cases of multiple sclerosis versus control group and to determine presence of any significant association. Methods: In this retrospective study, 30 cases of newly diagnosed multiple sclerosis were randomly selected and matched for age and sex with 30 controls. Demographics and serum vitamin D level for both groups were evaluated. Appropriate statistical analysis was performed to show any significant association. Results: An independent-samples t-test was conducted. There was a significant difference in Vitamin D level for MS (Mean=37.08, SD=17.63) and control group (Mean=58.103, SD=21.5323); p<0.05. Conclusion: Findings of this study suggest: 1. There is significant association between vitamin D deficiency and Multiple Sclerosis 2. Hypovitaminosis D may be a contributing factor in lowering the mean age of MS diagnosis. We propose early evaluation for vitamin D insufficiency in cases of MS and emphasis on restoring serum vitamin D to satisfactory levels as part of clinical management of MS. It would be worthwhile doing a large randomized trial to establish the safety and efficacy needed to promote large-scale vitamin D supplementation.