alexa IgA Nephropathy, Beta Thalassemia Minor, Psychosis and Deafness: A New Syndrome?
ISSN: 2161-0959

Journal of Nephrology & Therapeutics
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Case Report

IgA Nephropathy, Beta Thalassemia Minor, Psychosis and Deafness: A New Syndrome?

Sanda Mrabet1*, Latifa Bourkhis1, Soumaya Ben Abdelkarim2, Awatef Azzabi1, Dorsaf Zellama1, Safa Nouira1, Wissal Sahtout1, Yosra Guedri1, Moncef Mokni2 and Abdellatif Achour1

1Department of Nephrology, Dialysis and transplantation, Sahloul University Hospital, Sousse, Tunisia

2Department of Pathology, Farhat Hached University Hospital, Sousse, Tunisia

*Corresponding Author:
Sanda Mrabet
Department of Nephrology, Dialysis and Transplantation
Sahloul hospital, Sousse, Tunisia
Tel: +216 54 595 239
Fax: +216 73 367 451
E-mail: [email protected]

Received Date: May 14, 2015; Accepted Date: February 17, 2016; Published Date: February 24, 2016

Citation: Mrabet S, Bourkhis L, Abdelkarim SB, Azzabi A, Dorsaf Zellama et al. (2016) IgA Nephropathy, β Thalassemia Minor, Psychosis and Deafness: A New Syndrome?. J Nephrol Ther 6:237. doi:10.4172/2161-0959.1000237

Copyright: © 2016 Mrabet S, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

 

Abstract

A 43-year-old male was admitted to our hospital because of renal failure and arterial hypertension. He was followed from the age of 15 years for psychosis and had no familial history of disease. Investigations revealed sensorineural deafness, a microcytic hypochromic anemia with normal ferritin leading to the diagnosis of β thalassemia minor and nephrotic syndrome. Examination of the renal biopsy specimen demonstrated severe Ig A nephropathy. No classic cause of IgA nephropathy was found. Review of literature showed two previous reported cases of Ig A nephropathy associated with β thalassemia minor but without deafness or psychosis. We wonder through this case if an explanation to this association may be made by a genetic defect.

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