alexa IgY Antibodies for the Prevention and Treatment of Heli
ISSN: 2161-0703

Journal of Medical Microbiology & Diagnosis
Open Access

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Review Article

IgY Antibodies for the Prevention and Treatment of Helicobacter pylori Infections

Julia Zajac1, Andreas Schubert3, Terry Dyck2 and Christopher Oelkrug1*

1Fraunhofer Institute for Cell Therapy and Immunology (IZI), Leipzig, Germany

2IgY Immune Technologies and Life Sciences Inc., Thunder Bay, Canada

3Fraunhofer Project Centre for Biomedical Engineering and Advanced Manufacturing, McMaster University, Hamilton, Canada

*Corresponding Author:
Christopher Oelkrug
Fraunhofer Institute for Cell Therapy
and Immunology, Perlickstraße 1
04103 Leipzig, Germany
Tel: +49341355363121
Fax: +493413553683121
E-mail: [email protected]

Received Date: April 04, 2017 Accepted Date: April 19, 2017 Published Date: April 24, 2017

Citation: Zajac J, Schubert A, Dyck T, Oelkrug C (2017) IgY Antibodies for the Prevention and Treatment of Helicobacter pylori Infections. J Med Microb Diagn 6: 254. doi:10.4172/2161-0703.1000254

Copyright: © 2017 Zajac J, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

 

Abstract

Major progress has been made both in the field of vaccination and also in therapies against H. pylori infections in recent years. But, the increasing number of H. pylori infections and its resistance to current antibiotics has become a worldwide problem, due to the direct correlation between H. pylori infections and gastritis, gastric ulcers as well as cancer. In this regard, new alternative therapies or prevention methods turned into a global need. Therefore, an oral administration of chicken antibodies IgY specific to H. pylori can be very advantageous. Antibodies like anti-UreB IgYs or anti-VacA IgYs, produced by adult avian species immunized previously with UreB and VacA antigens respectively, are highly effective as a prophylaxis against H. pylori but as well as a treatment of already existing infection.

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