alexa Immediate Anterior Chamber Paracentesis with a 30-Gauge
ISSN: 2155-9570

Journal of Clinical & Experimental Ophthalmology
Open Access

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Research Article

Immediate Anterior Chamber Paracentesis with a 30-Gauge Needle for Acute Primary Angle Closure

Naris Kitnarong1*, Sumalee Boonyaleepun2, Darin Sakiyalak1, Ngamkae Ruangvaravate1 and Ankana Metheetrairut1

1Department of Ophthalmology, Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand

2Department of Ophthalmology, Faculty of Medicine, Sinakarinwirot University, Thailand

*Corresponding Author:
Naris Kitnarong
Department of Ophthalmology, Faculty of Medicine Siriraj Hospital
Mahidol University, 2 Prannok Road, Bangkoknoi
Bangkok 10700, Thailand
Tel: +662-419-8033
Fax: +662-411-1906

Received date: October 30, 2016; Accepted date: June 15, 2017; Published date: June 20, 2017

Citation: Kitnarong N, Boonyaleepun S, Sakiyalak D, Ruangvaravate N, Metheetrairut A (2017) Immediate Anterior Chamber Paracentesis with a 30-Gauge Needle for Acute Primary Angle Closure. J Clin Exp Ophthalmol 8:657. doi:10.4172/2155-9570.1000657

Copyright: © 2017 Kitnarong N, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.



Background: Primary angle-closure glaucoma (PACG) is more common among Asians than among Caucasians. Acute primary angle closure (APAC) is a serious associated complication in PACG patients. When conventional treatment fails, Anterior Chamber Paracentesis (ACP) can be performed to decrease IOP. Although slit knives are commonly used for performing ACP, other techniques can also be used to perform this procedure. Objective: To investigate the efficacy and safety of immediate anterior chamber paracentesis using a 30-gauge needle combined with conventional topical and systemic medications for the treatment of APAC. Materials and methods: This prospective study was conducted in 15 consecutive primary angle-closure glaucoma patients that presented with and who were treated for acute primary angle closure (APAC) at the Department of Ophthalmology, Siriraj Hospital, (Bangkok, Thailand) during the January 2015 to December 2015 study period. Patients were included if they were older than 18 years of age, if this was their first known attack of APAC, and if they had an IOP ≥ 40 mmHg. Results: Mean age of the 15 included participants (3 males, 12 females) was 61 years. Mean presenting IOP ± SD was 54.3 ± 11.6 mmHg. Twelve of 15 eyes had visual acuity worse than 6/18. Immediately after ACP, mean IOP ± SD was 7.5 ± 5.1 mmHg. None of the 15 included eyes were reactive to light prior to ACP. Mean pupil diameter was significantly reduced from baseline at 60 minutes after ACP (p=0.004) and was significantly smaller than baseline at 24 h after ACP (p=0.03). BCVA was improved to ≥ 6/18 in 11 and 12 eyes at 1 and 24 h after ACP, respectively. All patients had relief from symptoms immediately following ACP. No ACP-related complications were observed in any patient in this study. Conclusion: Immediate APC with a 30-guage needle is a safe and effective initial treatment for APAC. APC should be combined with conventional treatment with topical and/or systemic medications. APC yields rapid IOP reduction, dramatic relief of symptoms, and corneal clarity. APC may also improve response to further treatment, improve IOP control, and may reduce or eliminate the need for systemic medication.


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