alexa Immediate Memory and Electro Physiologic Effects of Pre
ISSN: 2329-9096

International Journal of Physical Medicine & Rehabilitation
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Case Report

Immediate Memory and Electro Physiologic Effects of Prefrontal Cortex Transcranial Direct Current Stimulation on a Chronic Traumatic Brain Injury Survivor: A Case Report

Therese M O’Neil-Pirozzi1*, Deniz Doruk2, Jennifer M Thomson3 and Felipe Fregni2

1Northeastern University & Spaulding Rehabilitation Hospital/Harvard Medical School 360, Huntington Avenue, 70 Forsyth Building, Room 103, Boston MA 02115, USA

2Spaulding Rehabilitation Hospital/Harvard Medical School 96 13th Street, Charlestown MA 02129, USA

3The University of Sheffield Western Bank, Sheffield, South Yorkshire, UK

*Corresponding Author:
Therese M O’Neil-Pirozzi
Northeastern University & Spaulding
Rehabilitation Hospital/Harvard Medical
School 360 Huntington Avenue
70 Forsyth Building, Room 103
Boston MA 02115, USA
Tel: 617-373-5750
Fax: 617-373-2239
E-mail: [email protected]

Received date: April 04, 2015; Accepted date: May 07, 2015; Published date: May 11, 2015

Citation: O’Neil-Pirozzi TM, Doruk D, Thomson JM and Fregni F (2015) Immediate Memory and Electro Physiologic Effects of Prefrontal Cortex Transcranial Direct Current Stimulation on a Chronic Traumatic Brain Injury Survivor: A Case Report. Int J Phys Med Rehabil 3:278. doi:10.4172/2329-9096.1000278

Copyright: ©2015 O’Neil-Pirozzi TM, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

 

Abstract

Ongoing memory impairment is a common long-term consequence of traumatic brain injury (TBI) that negatively impacts everyday function. Traditional rehabilitation to improve memory function focuses on use of external and/or internal behavioral memory strategies, the benefits of which are supported by varying levels of evidence. This case report examined immediate behavioral and electrophysiological effects of three conditions of left dorsolateral prefrontal cortex Transcranial direct current stimulation (tDCS) on auditory working memory in a chronic TBI survivor with persisting post-injury memory problems. Pre- and post-tDCS behavioral memory performance was measured, as were auditory event-related potentials (P300 activity) and power of alpha and theta EEG bands. Behavioral and electrophysiological results were specific to tDCS condition, with anodal tDCS, versus cathodal and sham, significantly enhancing memory function and related cortical activity. Rehabilitation implications of these findings are discussed.

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