Special Issue Article
Immunochromatographic Testing Method for Hepatitis B, C in Blood Donors
- *Corresponding Author:
- Olabowale Adefolake Omolade
Departments of Community Medicine and Primary Care
Public Health Laboratory Unit
Olabisi Onabanjo University
Sagamu, Ogun State, Nigeria
E-mail: [email protected]
Received Date: July 29, 2013; Accepted Date: November 08, 2013; Published Date: November 12, 2013
Citation: Adeyemi AA, Omolade OA, Raheem-Ademola RR (2013) Immunochromatographic Testing Method for Hepatitis B, C in Blood Donors. J Antivir Antiretrovir S3:005. doi: 10.4172/jaa.S3-005
Copyright: © 2013 Adeyemi AA, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Background: Hepatitis is an inflammatory condition of the liver and viral hepatitis is a conventional term used to denote hepatitis caused by hepatotrophic viruses (Hepatitis A-G). High prevalence of these viruses are reported in Nigeria. Hepatitis B and C may cause liver cirrhosis and they can be contacted through contaminated blood and blood products. Many blood banks in Nigeria screen for hepatitis B and C using immune-chromatographic screening method (Rapid test strip). This is because these strips are readily available in the market, cheap, requires no electricity for storage, special training or equipment before use. The intent of our study is to compare the sensitivity of this method using an advanced immunological method.
Method: 660 potential donors are tested for hepatitis B surface antigen (HBs Ag) and hepatitis C virus antibody using immune-chromatographic test strip and ELISA methods.
Result: We found out that 38 (5.7%) out of 660 subjects tested positive for HBS Ag using immunochromographic method while 71 (10.8%) were positive using ELISA. None is positive for hepatitis C antibody using immunochromatographic method while 4 (0.6%) subjects were positive using ELISA method.
Conclusion: Immunochromatographic method is not good enough to screen blood donors for hepatitis B and C.