Immunohistochemical Analysis of Dendritic Cells in Skin Lesions: Correlations with Survival Time
- *Corresponding Author:
- Oscar C
Cardiovascular Genetics Center
Gencardio Biomedical Research Institute of Girona (IDIBGI)
Marti and Julia Park Hospital (M -2) 17190, Salt-Girona, Spain
E-mail: [email protected]
Received date: June 03, 2016; Accepted date: June 12, 2016; Published date: June 20, 2016
Citation: Oscar C, Ramon B (2016) Molecular Autopsy in Unexplained Sudden Death. J Foren Path 1:e102. doi:10.4172/jfp.1000e102
Copyright: © 2016 Oscar C, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Wound age evaluation is one of the most challenging issues in forensic pathology. In the first minutes or hours, standard histological examination may not determine whether the wound was inflicted in the pre- or post-mortem period. Numerous studies about wound vitality are available in the literature. They have evaluated markers involved in coagulation or inflammation, using various methods such as enzymology, molecular biology or immunohistochemistry. This commentary is focused on the recent proposal to use mast cells and dendritic cells as cellular tools for the discrimination of vital and post mortem wounds.