Immunohistochemical Evaluation of Bcl-2 Oncoprotein in Buffalos Adrenal GlandHossam Fouad Attia1*, Gamal Hasan Abdel-Rahman2, Mohamed Abdu Nassan3, and Ahmed AbdelAziz Baiomy4
- *Corresponding Author:
- Hossam Fouad Attia
Histology and Cytology Department
Faculty of Veterinary Medicine
Benha University Egypt and Faculty of Applied Medical Science
Taif University KSA
E-mail: [email protected]
Received date: December 27, 2012; Accepted date: February 04, 2013; Published date: February 06, 2013
Citation: Attia HF, Abdel-Rahman GH, Nassan MA, Baiomy AA (2013) Immunohistochemical Evaluation of Bcl-2 Oncoprotein in Buffalo’s Adrenal Gland. J Cytol Histol 4:167. doi:10.4172/2157-7099.1000167
Copyright: © 2013 Attia HF, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
The present study was undertaken to correlate the immunohistochemical expression of Bcl-2 oncoprotein in buffalo’s adrenal gland in the young and old ages. Paraffin-embedded sections from the adrenal glands representing the young and old ages were immunostained for Bcl-2 oncoprotein. A higher percentage of Bcl-2 immunoreactivity was detected in the adrenal cortical cells of the buffaloes at young ages. The immunoreactivity was moderate in the adrenal cortical cells of the old ages. The degree of intensity was prominent in the zona reticularis than that of the other zones, while negative immunoreactivity in the cells of the adrenal medulla. In conclusion, the immunohistochemical expression of Bcl-2 oncoprotein in the young buffalo’s adrenal gland (antiapoptotic gene) was prominent than the old ages. So the incidence of apoptosis was prominent in the adrenal gland cortical cells of the old age than that the adrenal gland cortical cells of the young ages.