alexa Immunomodulation of Nile Tilapia, <em>Oreochromis niloticus</em>, by Nigella sativa and <em>Bacillus subtilis</em> | OMICS International | Abstract
ISSN: 2155-9546

Journal of Aquaculture Research & Development
Open Access

Like us on:

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations
700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Research Article

Immunomodulation of Nile Tilapia, Oreochromis niloticus, by Nigella sativa and Bacillus subtilis

Ahmad A Elkamel1* and Gamal M Mosaad2

1Fish Diseases and Management, Department of Animal Medicine, Faculty of Veterinary Medicine, Assiut University, Assiut, Egypt

2Animal Nutrition, Department of Animal and Clinical Nutrition, Faculty of Veterinary Medicine, Assiut University, Assiut, Egypt

*Corresponding Author:
Elkamel AA
Department of Animal Medicine
Faculty of Veterinary Medicine
Assiut University, Assiut , Egypt
E-mail: [email protected]

Received Date: July 02, 2012; Accepted Date: August 16, 2012; Published Date: August 26, 2012

Citation: Elkamel AA, Mosaad GM (2012) Immunomodulation of Nile Tilapia, Oreochromis niloticus, by Nigella sativa and Bacillus subtilis. J Aquacult Res Dev 3:147. doi:10.4172/2155-9546.1000147

Copyright: © 2012 Elkamel AA, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.


The aim of this study is to investigate the modulation of the immune system of Nile tilapia, Oreochromis niloticus,by the black cumin seeds, Nigella sativa, or Bacillus subtilis PB6 (CloSTAT) as feed additives. Four diet regimes, a basic (control), CloSTAT, nigella, or combination of the black cumin seeds and CloSTAT were formulated and used to feed fish for 30 successive days. Half of the fish were used to investigate some of the immune parameters as serum globulins, white blood cell counts, and phagocytic activities and phagocytic indices. The other half of fish was subjected to infection challenge with Aeromonas hydrophila to investigate the disease resistance ability of the fish received the feeding additives. Results showed that the serum globulins have significantly increased in fish received the combination diet, while white blood cells have significantly increased in fish fed with nigella or combination ration.Phagocytic activities and indices of the fish fed the combination ration were significantly higher than those of the control groups. The mortality rate of fish fed with nigella or combination ration and challenged with A. hydrophila were significantly lower than those that received the basic diet. The current study clearly demonstrated that black cumin,CloSTAT or both can be used to modulate the immune system of Nile tilapia to the favour of resistance to diseases.


Peer Reviewed Journals
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2018-19
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri & Aquaculture Journals

Dr. Krish

[email protected]

+1-702-714-7001Extn: 9040

Biochemistry Journals

Datta A


[email protected]

1-702-714-7001Extn: 9037

Business & Management Journals


porn sex

[email protected]

1-702-714-7001Extn: 9042

Chemistry Journals

Gabriel Shaw

Gaziantep Escort

[email protected]

1-702-714-7001Extn: 9040

Clinical Journals

Datta A


[email protected]

1-702-714-7001Extn: 9037


James Franklin

[email protected]

1-702-714-7001Extn: 9042

Food & Nutrition Journals

Katie Wilson

[email protected]

1-702-714-7001Extn: 9042

General Science

Andrea Jason

mp3 indir

[email protected]

1-702-714-7001Extn: 9043

Genetics & Molecular Biology Journals

Anna Melissa

[email protected]

1-702-714-7001Extn: 9006

Immunology & Microbiology Journals

David Gorantl

[email protected]

1-702-714-7001Extn: 9014

Materials Science Journals

Rachle Green

[email protected]

1-702-714-7001Extn: 9039

Nursing & Health Care Journals

Stephanie Skinner

[email protected]

1-702-714-7001Extn: 9039

Medical Journals


Nimmi Anna

[email protected]

1-702-714-7001Extn: 9038

Neuroscience & Psychology Journals

Nathan T


[email protected]

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

Ann Jose

[email protected]

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

[email protected]

1-702-714-7001Extn: 9042

© 2008- 2018 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version