alexa Immunosuppression Induced by HIV Infection
ISSN: 0974-8369

Biology and Medicine
Open Access

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Editorial

Immunosuppression Induced by HIV Infection

Mohamed G Elfaki*

Department of Infection and Immunity, King Faisal Specialist Hospital and Research Centre and Alfaisal University College of Medicine, Riyadh, Saudi Arabia

*Corresponding Author:
Mohamed G Elfaki
Department of Infection and Immunity
King Faisal Specialist Hospital & Research Centre
P.O. Box 3354, MBC 03, Riyadh 11211, Kingdom of Saudi Arabia
Tel: +966546271771
Fax: +9660114424519
E-mail: [email protected]

Received date: July 17, 2014; Accepted date: August 20, 2014; Published date: August 27, 2014

Citation: Mohamed G. Elfaki (2014) Immunosuppression Induced by HIV Infection. Biol Med 6:e111 doi:10.4172/0974-8369.1000e111

Copyright: © 2014 M.G. Elfaki, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

 

Abstract

Immunosuppression due to HIV infection is a resultant of several factors including defective innate signaling pathways, increased viral replication and virus load, gradual loss of peripheral CD4+T cells and depletion of T lymphocytes at mucosal sites that collectively lead to progressive immune deficiency and AIDS development. T cells derived from HIV patients were anergic and failed to mount a robust adaptive immune response. The host, on the other hand, becomes vulnerable to opportunistic infections such as tuberculosis and AIDS-related cancer such as Kaposi sarcoma, non-Hodgkin lymphoma, and cervical cancer with remarkable level of immunosuppression. Elucidation of the various mechanisms involved in these immunologic perturbations is necessary to understand HIV pathogenesis for an effective immunotherapy.

Keywords

Share This Page

Additional Info

Loading
Loading Please wait..
 
Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri, Food, Aqua and Veterinary Science Journals

Dr. Krish

[email protected]

1-702-714-7001 Extn: 9040

Clinical and Biochemistry Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Business & Management Journals

Ronald

[email protected]

1-702-714-7001Extn: 9042

Chemical Engineering and Chemistry Journals

Gabriel Shaw

[email protected]

1-702-714-7001 Extn: 9040

Earth & Environmental Sciences

Katie Wilson

[email protected]

1-702-714-7001Extn: 9042

Engineering Journals

James Franklin

[email protected]

1-702-714-7001Extn: 9042

General Science and Health care Journals

Andrea Jason

[email protected]

1-702-714-7001Extn: 9043

Genetics and Molecular Biology Journals

Anna Melissa

[email protected]

1-702-714-7001 Extn: 9006

Immunology & Microbiology Journals

David Gorantl

[email protected]

1-702-714-7001Extn: 9014

Informatics Journals

Stephanie Skinner

[email protected]

1-702-714-7001Extn: 9039

Material Sciences Journals

Rachle Green

[email protected]

1-702-714-7001Extn: 9039

Mathematics and Physics Journals

Jim Willison

[email protected]

1-702-714-7001 Extn: 9042

Medical Journals

Nimmi Anna

[email protected]

1-702-714-7001 Extn: 9038

Neuroscience & Psychology Journals

Nathan T

[email protected]

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

John Behannon

[email protected]

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

[email protected]

1-702-714-7001 Extn: 9042

 
© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
adwords