alexa Impact of Gender in the Quality of Life of Patients with Rheumatoid Arthritis | OMICS International
ISSN: 2167-7921

Journal of Arthritis
Open Access

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Research Article

Impact of Gender in the Quality of Life of Patients with Rheumatoid Arthritis

Aurrecoechea E1*, llorcadiaz J2, Diezlizuain ML3, Mcgwin G. Jr4 and Calvo-alen J1
1Rheumatology Section, Hospital Universitario Sierrallana, Torrelavega, Cantabria, Spain
2Division of Epidemiology and Computational Biology, School of Medicine, Universidad de Cantabria, Spain
3Radiology Department, Radiology Section, Hospital Universitario Sierrallana, Torrelavega, Cantabria, Spain
4Professor and Vice Chair of Epidemiology, Faculty of the University of Alabama in Birmingham, USA
Corresponding Author : Elena Aurrecoechea
Hospital Sierrallana
Manuel Teira s.n. Torrelavega-39300 Cantabria, Spain
Tel: + 34-942-847400
Fax: + 34-942-847415
E-mail: [email protected]
Received July 28, 2015; Accepted August 01, 2015; Published August 10, 2015
Citation: Aurrecoechea E, llorcadiaz J, Diezlizuain ML, Mcgwin G, Calvo-alen J (2015) Impact of Gender in the Quality of Life of Patients with Rheumatoid Arthritis. J Arthritis 4:160. doi:10.4172/2167-7921.1000160
Copyright: © 2015 Aurrecoechea E, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Abstract

Objective: To evaluate the impact of gender in the quality of life (QOL) of rheumatoid arthritis (RA) patients and the factors associated with such effect.

Methods: Seventy RA patients of each gender were cross-sectionally evaluated as per pre-established protocol: medical history review, standardized disease severity measurements, and comprehensive psychological and disease-related behaviors and coping strategies assessment. QOL was assessed with the SF-36 questionnaire. Univariable and multivariable analyses were performed to examine the contribution of gender and other variables to QOL.

Results: Both groups were comparable regarding age at diagnosis, disease duration, disease activity, and radiological damage. Women showed higher functional impairment (mHAQ: 0.89 ± 2.6 vs. 0.22±0.9, p=0.04), higher prevalence of depression and of osteoporosis, as well as higher scores in the Beck scale (10.7 ± 7.52 vs. 7.8 ± 6.8, p=0.016) but not in other psychological and behavioral variables. In the SF-36, women also showed a greater impairment than men in physical functioning (PF) (57.7 ± 22.1 vs. 67.3 ± 22.7; p=0.01), general health (GH) (41.3 ± 21.7 vs. 50.0 ± 24.3, p=0.02), mental health (MH) (63.7 ± 22.0 vs. 71.8 ± 21.1, p=0.02) and physical component summary score (PCS) (39.3 ± 8.9 vs. 42.4 ± 9.3, p=0.04). Female gender remained significantly associated with poorer PF in multivariable analysis even after adjusting for the Beck Scale (p=0.08), and osteoporosis (p=0.09).

Conclusions: Female RA patients have lower QOL levels than their male counterparts. Depression and osteoporosis may play an important role in this effect. These data should be taken into account in the management of these patients.

Main findings -Gender medicine is a new paradigm of studying chronic diseases. -RA patients of both genders present similar biological and immunological features but women experience poorer QOL. -This is the first study on gender differences in RA examining two sets of RA patients evaluated comprehensively using a standardized protocol inclusive of clinical, ancillary, functional, QOL and psychosocial variables.

Keywords

Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri & Aquaculture Journals

Dr. Krish

[email protected]

1-702-714-7001Extn: 9040

Biochemistry Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Business & Management Journals

Ronald

[email protected]

1-702-714-7001Extn: 9042

Chemistry Journals

Gabriel Shaw

[email protected]

1-702-714-7001Extn: 9040

Clinical Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Engineering Journals

James Franklin

[email protected]

1-702-714-7001Extn: 9042

Food & Nutrition Journals

Katie Wilson

[email protected]

1-702-714-7001Extn: 9042

General Science

Andrea Jason

[email protected]

1-702-714-7001Extn: 9043

Genetics & Molecular Biology Journals

Anna Melissa

[email protected]

1-702-714-7001Extn: 9006

Immunology & Microbiology Journals

David Gorantl

[email protected]

1-702-714-7001Extn: 9014

Materials Science Journals

Rachle Green

[email protected]

1-702-714-7001Extn: 9039

Nursing & Health Care Journals

Stephanie Skinner

[email protected]

1-702-714-7001Extn: 9039

Medical Journals

Nimmi Anna

[email protected]

1-702-714-7001Extn: 9038

Neuroscience & Psychology Journals

Nathan T

[email protected]

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

Ann Jose

[email protected]

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

[email protected]

1-702-714-7001Extn: 9042

 
© 2008- 2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version