Impaired Cardiac Function in Cardiac-Specific SIRT1-Deficient Mice
Chief Physician, Cardiology Deptartment, Chinese PLA General Hospital, Beijing, P.R.China
- *Corresponding Author:
- Feng Cao
Associate Director, Chief Physician
Cardiology Deptartment, Chinese PLA General Hospital
28# Fuxing Street, Beijing, 100853,P.R.China
E-mail: [email protected]
Received Date: November 01, 2014; Accepted Date: November 02, 2014; Published Date: November 04, 2014
Citation: Feng Cao (2014) Impaired Cardiac Function in Cardiac-Specific SIRT1-Deficient Mice. Cao, J Cell Sci Ther 2014 5:I101. doi: 10.4172/2157-7013.1000I101
Copyright: © 2014 Cao F. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use,distribution, and reproduction in any medium, provided the original author and source are credited.
Cardiac specific SIRT1 knockout mice were generated through the Cre/loxP system. Briefly, loxP-SIRT1 mice and Myh6-Cre mice were crossed to get SIRT1+/- mice.