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Importance of Case Reports in Medical Literature | OMICS International | Abstract
ISSN: 2165-7920

Journal of Clinical Case Reports
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Importance of Case Reports in Medical Literature

Rehman HU*
Clinical Associate Professor, University of Saskatchewan, Regina Qu’Appelle Health Region, Suite 100, 2550, 12th Avenue, Regina, SK, S4P 3X1, Canada
Corresponding Author : Rehman HU
Clinical Associate Professor
University of Saskatchewan
Regina Qu’Appelle Health Region
Suite 100, 2550, 12th Avenue
Regina, SK, S4P 3X1, Canada
E-mail: [email protected]
Received November 26, 2011; Accepted November 29, 2011; Published December 08, 2011
Citation: Rehman HU (2011) Importance of Case Reports in Medical Literature. J Clinic Case Reports 1:e101. doi:10.4172/2165-7920.1000e101
Copyright: © 2011 Rehman HU. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.


In a world of evidence-based medicine, where randomized trials are considered the gold standard of evidence, case reports and case series are at the bottom of this hierarchy. Whereas randomized control trials assess the level of uncertainty about a benefit or harm, case reports have a different fundamental function. Case reports typically highlight extremely unusual and novel findings. Case reports can rarely prove causation but generate a new hypothesis and stimulate further research. Only once a hypothesis is generated (a function of case reports), randomized trials will do final evaluation of therapies or tests. Case reports or case series are the only way to bring a new disease to the attention of the medical community. AIDS is a good example in the recent history, when astute physicians noticed immunodeficiency related diseases in a patient who had no reason to be immunodeficient [1]. New side effects of drugs are also usually reported in case reports or case series. The first case reports that suggested a link between the use of appetite suppressants and valvular heart disease were published in 1997


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