Importance of High Grade Transformation and Translocations in Salivary Gland NeoplasmsHenrik Hellquist*
Department of Biomedical Sciences and Medicine, Algarve University, Faro, Portugal
- *Corresponding Author:
- Henrik Hellquist
MD, PhD, SAPath (Stockholm), FRCPath (London)
Professor, Department of Biomedical Sciences and Medicine
Algarve University, Faro, Portugal
Tel: +351 289 800 000
E-mail: [email protected]
Received date: December 29, 2016; Accepted date: January 11, 2017; Published date: January 13, 2017
Citation: Hellquist H (2017) Importance of High Grade Transformation and Translocations in Salivary Gland Neoplasms. Single Cell Biol 6:156. doi:10.4172/2168-9431.1000156
Copyright: © 2017 Hellquist H. This is an open-access article distributed under the terms of the creative commons attribution license, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
The concept of high grade transformation in human neoplasms was introduced in 1971 by the report demonstrating that 33 of 370 cases of well differentiated (low-grade) chondrosarcomas contained areas of a high-grade sarcoma. Currently at least 23 different types of primary salivary carcinomas are recognized, some of low and others of high grade malignancy.