alexa Importance to Vaccination Against Rabies in Travellers
ISSN: 2157-7560

Journal of Vaccines & Vaccination
Open Access

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Importance to Vaccination Against Rabies in Travellers to Areas of Risk

Concepción Ladrón de Guevara García*
National Reference Center for Adults Imported Tropical Pathology and Pediatrics, Spain
*Corresponding Author : Concepción Ladrón de Guevara García
National Reference Center for Adults Imported
Tropical Pathology and Pediatrics
RICET, Hospital CarlosIII, C/Sinesio Delgado 10
Madrid, Spain
Tel: 00-34-630923619
Email: [email protected]
Received date: Jan 24, 2016; Accepted date: Mar 07, 2016; Published date: Mar 10, 2016
Citation: García CLDG (2016) Importance to Vaccination Against Rabies in Travellers to Areas of Risk. J Vaccines Vaccin 7:311. doi: 10.4172/2157-7560.1000311
Copyright: © 2016 García CLDG, This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.


A patient returned from Algeria showing a grade III wound (WHO standard) produced by a dog bite, was treated with rabies nerve tissue vaccines (NTVs) lacked the rabies immunoglobin, and developed a visible local reaction to the vaccine.
The last WHO position paper (2010) recommends replacing nerve-tissue vaccines with CCVs. The nerve tissue vaccines induce more-severe adverse reaction sand are less immunogenic than CCVs.
It should be assessed in travellers to areas of risk, pre-exposure vaccination, and eliminated the need to the use of rabies globulin post exposition, and avoid as much as possible the use of of nerve-tissue vaccines.


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