Improved Image Analysis of DETECHIPÃÂ® Allows for Increased Specificity in Drug Discrimination
Andy Smith, Abby Jackson*, Mark V Wilson, Mitch Trauernicht and Andrea E. Holmes
Doane College, Department of Chemistry, 1014 Boswell Avenue, Crete, NE 68333, USA
- *Corresponding Author:
- Abby Jackson
PhD, Department of Chemistry
1014 Boswell Ave. Crete
NE 68333, USA
E-mail: [email protected]
Received date: June 21, 2012; Accepted date: July 26, 2012; Published date: July 30, 2012
Citation: Smith A, Jackson A, Wilson MV, Trauernicht M, Holmes AE (2012) Improved Image Analysis of DETECHIP® Allows for Increased Specificity in Drug Discrimination. J Forensic Res 3:161. doi:10.4172/2157-7145.1000161
Copyright: © 2012 Smith A, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
DETECHIP® is a novel molecular sensing array being developed for the detection and identification of a variety of compounds including controlled substances. This easy to use technology has the ability to produce a unique identifying binary code for each substance tested. Original analysis methodology relied on human vision to classify color and fluorescence changes within the array. New digital color image analysis techniques using Red-Green-Blue (RGB) color values provided a higher degree of specificity and greater consistency. This image analysis technique was able to detect more subtle changes in color and was therefore able to properly discriminate between substances that previously produced identical codes. This technique was also expanded to analyze changes in RGB color values individually, increasing the length of the code to 48 digits and therefore potentially providing a further increase in specificity. To show the applicability of this new method, a blind study was performed, correctly identifying two unknown analytes.