alexa Improved Primary Patency Rate of Hemodialysis Arterovenous Grafts Associated With Modified Stretch e-PTFE Vascular Grafts (Gore) by Compliant ePTFE Cuff
ISSN: 2161-1076

Surgery: Current Research
Open Access

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Research Article

Improved Primary Patency Rate of Hemodialysis Arterovenous Grafts Associated With Modified Stretch e-PTFE Vascular Grafts (Gore) by Compliant ePTFE Cuff

Massimiliano Gessaroli*, Silvia Massini and Salvatore Tarantini

Vascular and Endovascular Unit, Infermi Hospital, Rimini, Italy

*Corresponding Author:
Massimiliano Gessaroli
Vascular and Endovascular Unit
Infermi Hospital via Settembrini
2 47900 Rimini - Italy
Tel: +390541705687
Fax: +390541705680
E-mail: [email protected]

Received date: February 23, 2012; Accepted date: April 19, 2012; Published date: April 20, 2012

Citation: Gessaroli M, Massini S, Tarantini S (2012) Improved Primary Patency Rate of Hemodialysis Arterovenous Grafts Associated With Modified Stretch e-PTFE Vascular Grafts (Gore) by Compliant ePTFE Cuff. Surgery Curr Res 2:115. doi:10.4172/2161-1076.1000115

Copyright: © 2012 Gessaroli M, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.



Purpose: The aim of this study was to value the performance of a modified commercially available longitudinal stretch expanded polytetrafluoroethylene (ePTFE) vascular Gore (W.L.Gore & Associates, Flagstaff, Arizona) graft (either Intering or heparin-bonded Propaten) with an added handmade compliant ePTFE cuff in arterovenous grafts (AVG) for hemodialysis, valuing the primary patency rate at 12 months.
Methods: 25 patients consecutively underwent AVG’s with 8 modified stretch Intering grafts (mIG) and 17 modified stretch Propaten grafts (mPG). The modified grafts were obtained during surgical procedures assembling to the major host of a tapered stretch (longitudinal) ePTFE hemodialysis Gore graft, an hand-made cuff of the same material but turned at 90° to obtain a radial stretch (previously reported in experimental animal study). Primary patency rate of these modified grafts was evaluated at 12 months and the results compared with our previous experience: 60 consecutive cases with the same unmodified grafts (53 Intering and 7 Propaten grafts).
Results: In 25 patients with the modified grafts the cumulative primary patency rate of arterovenous grafts at 12 months was 91.3% with a one year mortality of 12%, while in our previous consecutive experience, primary patency and mortality rates in 60 patients with unmodified grafts were 60.4% and 11.7%, respectively. Valuing the overall combined primary patency rate of arterovenous grafts of the two groups (modified vs. unmodified grafts) with Kaplan Meyer curve and Logrank test the difference was statistically significant: Chi square=7.115, p=0.007. On the contrary analyzing the two subgroups with modified grafts ( mIG vs. mPG) primary patency rates were 100% in both at 6 months, 87.5% and 94.1%, respectively at 12 months (statistically not significant).
Conclusions: The preliminary resuts of modified stretch ePTFE vascular grafts with compliant ePTFE cuff significantly seem to improve the vascular access graft patency, independently by the used stretch graft (heparinbonded or not).

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