In Vitro Antimicrobial Activity of Natural Essence and Distilled Extract of Bergamot against Drug Resistance Clinical Isolates
Angela Q*, Paola M, Vito M, Giuseppe C, Settimo BG, Carla LM and Alfredo F
University “Magna Graecia”, Catanzaro, Italy
- Corresponding Author:
- Angela Q
University “Magna Graecia”
Viale Europa, 88100 Catanzaro, Italy
E-mail: [email protected]
Received April 01, 2016; Accepted May 09, 2016; Published May 12, 2016
Citation: Angela Q, Paola M, Vito M, Giuseppe C, Settimo BG, et al. (2016) In Vitro Antimicrobial Activity of Natural Essence and Distilled Extract of Bergamot against Drug Resistance Clinical Isolates. Med Aromat Plants S3:007. doi:10.4172/2167-0412.S3-007
Copyright: © 2016 Angela Q, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Bergamot (Citrus bergamia) belongs to the Citreae tribe in the Aurantioideae subfamily of the Rutaceae plant family cultivated almost exclusively along the coast of the Calabria region, Southern Italy. Bergamot essential oil is widely employed in cosmetics such as in aromatherapy and its antimicrobial effects against bacteria, yeasts and virus are also demonstrated. This study evaluates the “in vitro” antimicrobial activity of natural essence and distilled extract of bergamot on drug resistance pathogens isolated from clinical specimens of patients admitted to University Hospital of Catanzaro, Italy. Bactericidal and fungicidal activity was analyzed using a micro well dilution assay and the efficacy of tested substances was verified by alcidine orange staining procedures and co focal microscopy. Data revealed that the distilled extract of bergamot possessed greatest antimicrobial efficacy when compared with essential oil particularly against drug resistant Gram negative bacteria such as Acinetobacter Baumann, Stenotrophomonas maltophilia, Escherichia coli and Klebsiella pneumoniae responsible for nosocomial infections representing a worldwide public health problem. This study suggests that alternative antimicrobial substances as well as distilled extract of bergamot could be of great utility to prevent microbial contamination on hospital devices and healthcare personnel hand skin.