alexa In Vitro Evaluation of Antimicrobial Effect of Extracts of Medicinal Plant’s Leaves | OMICS International
ISSN: 2161-0703

Journal of Medical Microbiology & Diagnosis
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Research Article

In Vitro Evaluation of Antimicrobial Effect of Extracts of Medicinal Plant’s Leaves

Ale Zehra*, Syed Baqir Shyum Naqvi and Syeda Qadam Ali

Department of Pharmaceutics, Faculty of Pharmacy, University of Karachi, Pakistan

Corresponding Author:
Ale Zehra
Department of Pharmaceutics
Faculty of Pharmacy, University of Karachi, Pakistan
Tel: 92-03462757106
E-mail: [email protected]

Received date: April 13, 2016; Accepted date: July 02, 2016; Published date: July 07, 2016

Citation: Zehra A, Naqvi SBS, Ali SQ (2016) In Vitro Evaluation of Antimicrobial Effect of Extracts of Medicinal Plant’s Leaves. J Med Microb Diagn 5:236. doi:10.4172/2161-0703.1000236

Copyright: © 2016 Zehra A, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Abstract

Abstract

In ancient and modern epoch, aerial parts of herbal plants have been broadly used for the treatment of primary health care and variety of ailment across the world depends on geographical cultivation. Now a day’s researcher focuses their attention to explore the plants having broad spectrum therapeutic activity. On the basis of medicinal plant activity surveillance, the core goal step of current study is to evaluate the susceptible antimicrobial activity of crude 50% hydro alcoholic extract of leaves of different folk medicinal plant i.e Ocimum basilicum L., Cymbopogon citratus (DC.) Stapf., Olea europaea L., Eucalyptus camaldulensis Dehnh. against different clinical isolates (Enterococcus faecalis, Escherichia coli, Klebsiella pneumoniae, Bacillus subtilis, Pseudomonas aeruginosa, Staphylococcus aureus, Staphylococcu epidermidis, Salmonella typhi and Candida albican) of microbial disease so as to trip up on the other alternatives and overcome the upcoming era of increasing microbial resistance. These isolates were collected from different hospitals and pathological laboratories of Karachi, Pakistan. Extract were obtain by soaking the leaves in 50% methanol and then vacuum dried through Rotavapor while the antimicrobial activity were evaluated by well diffusion method. Overall outcome of current study endorse that among selected herbs, Olea europea possessed broad spectrum antimicrobial activity. Further investigation is needed to develop formulation from the same plant. It’s timely need to explore the antimicrobial activity of other herbs also.

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